Leveraging Hematopoietic Cell Transplant Data and Biorepository Resources at the Center for International Blood and Marrow Transplant Research to Improve Patient Outcomes

被引：2

作者：

Bolon, Yung-Tsi ^{[1
]}

Atshan, Rasha ^{[2
]}

Allbee-Johnson, Mariam ^{[2
]}

Estrada-Merly, Noel ^{[2
]}

Auletta, Jeffery J. ^{[1
,5
]}

Broglie, Larisa ^{[2
,3
]}

Cusatis, Rachel ^{[2
]}

Page, Kristin M. ^{[2
,3
]}

Phelan, Rachel ^{[2
,3
]}

Sajulga Jr, Ray ^{[1
,2
]}

Shaw, Bronwen E. ^{[2
]}

Spahn, Ashley ^{[1
]}

Steinert, Patricia ^{[2
]}

Stewart, Valerie ^{[1
]}

Vierra-Green, Cynthia ^{[1
]}

Lee, Stephanie J. ^{[1
,4
]}

Spellman, Stephen R. ^{[1
]}

机构：

[1] NMDP, CIBMTR Ctr Int Blood & Marrow Transplant Res, Minneapolis, MN USA

[2] Med Coll Wisconsin, CIBMTR Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI USA

[3] Med Coll Wisconsin, Dept Pediat, Div Pediat Hematol Oncol Blood & Marrow Transplant, Milwaukee, WI USA

[4] Fred Hutchinson Canc Ctr, Seattle, WA USA

[5] Nationwide Childrens Hosp, Hematol Oncol BMT & Infect Dis, Columbus, OH USA

来源：

TRANSPLANTATION AND CELLULAR THERAPY | 2024年 / 30卷 / 09期

基金：

美国国家卫生研究院;

关键词：

Hematopoietic cell; transplant; Biorepository; Resources; HLA-MATCHING GUIDELINES; VALIDATION; MORTALITY; HLA-DPB1; TRENDS;

D O I：

10.1016/j.jtct.2024.06.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hematopoietic cell transplantation (HCT) has undergone many advances over the decades. Trends in HCT utilization have been impacted by research based on the data and samples collected by the Center for International Blood and Marrow Transplant Research (CIBMTR). Here, we provide a summary report of the CIBMTR Biorepository resource and describe the biospecimen inventory along with collection and request procedures. The diversity captured in this inventory reflects transplant activity, and these samples can be leveraged for secondary analyses to generate more data and insights to advance the field. We describe how our resources have already impacted HCT practice and elaborate on possibilities for further collaboration and utilization to maximize capabilities and research opportunities. Hematopoietic cell transplant data and biorepository resources at the CIBMTR have been and continue to be leveraged to improve patient outcomes. (c) 2024 Published by Elsevier Inc. on behalf of The American Society for Transplantation and Cellular Therapy.

引用

页数：22

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