A fatal snakebite envenomation due to King cobra ( Ophiophagus hannah) ) in the Eastern Visayas, Philippines

被引:0
|
作者
Arrieta, Rustan [1 ]
Aoki, Yoshihiro [2 ,3 ]
Tan, Mariedel A. [4 ]
Sarsalijo, Mardie S. [4 ]
Sarmiento, Marvin Jay [5 ,6 ,7 ]
Paghubasan, Jonathan [1 ]
Tiglao, Patrick Joseph [5 ,8 ]
Yoshimura, Ken [9 ]
Sakai, Atsushi [9 ]
Agosto, Lourdes C. [4 ]
机构
[1] Eastern Visayas Med Ctr, Dept Emergency Med, Tacloban, Philippines
[2] Nagasaki Univ Hosp, Acute & Crit Care Ctr, Coordinat Off Emergency Med & Int Response, Nagasaki, Japan
[3] Nagasaki Univ, Sch Trop Med & Global Hlth, Nagasaki, Japan
[4] Eastern Visayas Med Ctr, Poison Control Ctr, Tacloban, Philippines
[5] Philippine Toxinol Soc Inc, Manila, Philippines
[6] Microbiol Lab Inc Evangelista, Crocodylus Porosus Philippines Inc, Makati, Philippines
[7] Univ Philippines Los Banos, Los Banos, Philippines
[8] Univ Philippines, Philippine Gen Hosp, Dept Emergency Med, Manila, Philippines
[9] Japan Snake Inst, Gunma, Japan
关键词
Antivenom; King cobra; Neglected tropical diseases; Neurotoxicity; Ophiophagus hannah; Respiratory resuscitation;
D O I
10.1016/j.toxicon.2024.107751
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This report details a documented case of fatal King cobra ( Ophiophagus hannah) ) envenomation in the Philippines. A 46-year-old woman from a mountainous town in Leyte was bitten on her left thigh by a snake. Despite receiving prompt medical attention, including administration of fluids and oxygen, she went into arrest and succumbed within 2.5 hours of the bite. Inadequate pre-hospital care, including endotracheal intubation and assisted ventilation, highlights a notable gap in emergency medical services. Photographic evidence, verified by a herpetologist, confirmed the involvement of a King cobra, with venom presenting with a swift and lethal systemic effect that led to the patient's demise, despite minimal local manifestations. This incident accentuates the urgent need for accessible, effective antivenom and improved snakebite management protocols in the Philippines. It also calls for heightened awareness and preparedness among pre-hospital healthcare providers and the public, alongside advocating for more research into snakebite envenomation.
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页数:3
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