ZnO Nanorod: An Efficient Reusable Catalyst for One-pot Multicomponent C-C Bond Formation Reactions Involving Isatins

In the present study we have disclosed here that ZnO nanorod (ZnO-NR) can effectively be used as a catalyst for various C-C bond formation reactions, i. e. allylation, as well as one-pot three components conjugate addition and Knoevenagel-allylation of isatins. The corresponding products were obtained with good to excellent yields under solvent-free conditions in most cases at RT. The catalyst was successfully recycled for up to five cycles for allylation reaction and one pot three components Knoevenagel-allylation reaction of isatin. X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) were used to characterize the structure and morphology of the catalyst. The present study demonstrated the catalytic efficacy of ZnO nanorod for allylation reaction, one-pot three-component conjugate addition, and Knoevenagel -allylation of isatins under ambient conditions. image