In-situ eco-friendly synthesis of a biomimetic robust antibacterial nanohybrid via catecholamine-induced metallization

Antimicrobial resistance and biofilm formation on various surfaces pose serious economic and health threats. Silver nanoparticles (Ag NPs) are well known for their antibacterial application. However, the chemical synthesis of Ag NPs is not environmentally friendly and the antibacterial activity is very low. In this manuscript, we used a new technique, catecholamine-induced metallization, to prepare a robust antibacterial nanohybrid, silver-polydopamine (Ag-PDA) nanohybrid. The antibacterial power of the nanohybrid is higher than the Ag NPs due to the synergistic effect of polydopamine (PDA). The 62.5 ppm of Ag-PDA particles inhibit >90 % of the bacterial growth. The bacterial attachment on a surface can be reduced by 99 % using the particle. In this manuscript, we report the synthesis, characterization, antibacterial, and anti-biofilm effects of Ag-PDA particles.