Benchmarking a universal smoking machine adaptor for tobacco product testing

被引:0
|
作者
El-Hellani, Ahmad [1 ,2 ]
Watson, Clifford H. [3 ]
Huang, Michelle [3 ]
Wilson, Clark W. [2 ,4 ]
Fleshman, Clint C. [2 ,4 ]
Tran, Hang [3 ]
Chafin, Dana [3 ]
McGuigan, Megan [3 ]
Cardenas, Roberto Bravo [3 ]
Petitti, Ryan [5 ]
Pancake, Mary [5 ]
Bennett, Chad [6 ]
Mays, Darren [2 ,7 ]
Keller-Hamilton, Brittney L. [2 ,7 ]
Jones, Jeremy [8 ]
Ye, Wei [9 ]
Schaff, Jason [9 ]
Borthwick, Robert P. [9 ]
Williamson, Raymond L. [9 ]
Wagener, Theodore L. [2 ,7 ]
Brinkman, Marielle C. [2 ,4 ]
机构
[1] Ohio State Univ, Coll Publ Hlth, Div Environm Hlth Sci, Columbus, OH 43210 USA
[2] Ohio State Univ, Ctr Tobacco Res, Comprehens Canc Ctr, Columbus, OH 43210 USA
[3] Ctr Dis Control & Prevent, Tobacco Prod Lab, Atlanta, GA USA
[4] Ohio State Univ, Coll Publ Hlth, Div Epidemiol, Columbus, OH 43210 USA
[5] Ohio State Univ, Ctr Design & Mfg Excellence, Columbus, OH 43210 USA
[6] Ohio State Univ, Drug Dev Inst, Comprehens Canc Ctr, Med Chem Shared Resource, Columbus, OH 43210 USA
[7] Ohio State Univ, Dept Internal Med, Columbus, OH 43210 USA
[8] Produced Better, Columbus, OH USA
[9] US FDA, Ctr Tobacco Prod, Silver Spring, MD USA
关键词
Carcinogens; Electronic nicotine delivery devices; Non-cigarette tobacco products; Smoking topography; Surveillance and monitoring; MAINSTREAM SMOKE; NICOTINE; EXPOSURE; MENTHOL; YIELDS;
D O I
10.1136/tc-2023-058517
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Significance Characterisation of tobacco product emissions is an important step in assessing their impact on public health. Accurate and repeatable emissions data require that a leak-tight seal be made between the smoking or vaping machine and the mouth-end of the tobacco product being tested. This requirement is challenging because of the variety of tobacco product mouth-end geometries being puffed on by consumers today. We developed and tested a prototype universal smoking machine adaptor (USMA) that interfaces with existing machines and reliably seals with a variety of tobacco product masses and geometries.Methods Emissions were machine-generated using the USMA and other available adaptors for a variety of electronic cigarettes (n=7 brands), cigars (n=4), cigarillos (n=2), a heated tobacco product, and a reference cigarette (1R6F), and mainstream total particulate matter (TPM) and nicotine were quantified. Data variability (precision, n >= 10 replicates/brand) for all products and error (accuracy) from certified values (1R6F) were compared across adaptors.Results TPM and nicotine emissions generated using the USMA were accurate, precise and agreed with certified values for the 1R6F reference cigarette. Replicate data indicate that USMA repeatability across all tobacco products tested generally meets or exceeds that from the comparison adaptors and extant data.Conclusion The USMA seals well with a variety of combustible tobacco products, e-cigarettes with differing geometries and plastic-tipped cigarillos. Variability for all measures was similar or smaller for the USMA compared with other adaptors.
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页数:8
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