Advances in the treatment of diabetic peripheral neuropathy by modulating gut microbiota with traditional Chinese medicine

被引:0
|
作者
Li, Ye-Yao [1 ]
Guan, Rui-Qian [2 ]
Hong, Zhi-Bo [1 ]
Wang, Yao-Lei [1 ]
Pan, Li-Min [1 ]
机构
[1] Heilongjiang Univ Chinese Med, Affiliated Hosp 2, Dept Endocrinol, 411 Guogeli Ave, Harbin 150001, Heilongjiang, Peoples R China
[2] Heilongjiang Univ Chinese Med, Affiliated Hosp 2, Dept Tuina, Harbin 150001, Heilongjiang, Peoples R China
关键词
Diabetes; Peripheral neuropathy; Traditional Chinese medicine; Gut microbiota; Diabetic foot ulcer; Treatment; MELLITUS;
D O I
10.4239/wjd.v15.i8.1712
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetic peripheral neuropathy (DPN) is one of the strongest risk factors for diabetic foot ulcers (neuropathic ulcerations) and the existing ulcers may further deteriorate due to the damage to sensory neurons. Moreover, the resulting numbness in the limbs causes difficulty in discovering these ulcerations in a short time. DPN is associated with gut microbiota dysbiosis. Traditional Chinese medicine (TCM) compounds such as Shenqi Dihuang Decoction, Huangkui Capsules and Qidi Tangshen Granules can reduce the clinical symptoms of diabetic nephropathy by modulating gut microbiota. The current review discusses whether TCM compounds can reduce the risk of DPN by improving gut mic-robiota.
引用
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页数:6
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