Dynamic modelling of EWS::FLI1 fluctuations reveals molecular determinants of phenotypic tumor plasticity and prognosis in Ewing sarcoma

被引:0
|
作者
Suresh, Veveeyan
Hafemeister, Christoph
Grissenberger, Sarah
Sturtzel, Caterina
Aranaz, Florencia Cidre
Grunewald, Thomas
Sastre, Ana
Alonso, Javier
Distel, Martin
Halbritter, Florian
Kovar, Heinrich
Fock, Valerie
机构
关键词
D O I
10.1158/1538-7445.PEDIATRIC24-A017
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A017
引用
收藏
页数:3
相关论文
共 50 条
  • [1] EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma
    Apfelbaum, April A.
    Wu, Feinan
    Hawkins, Allegra G.
    Magnuson, Brian
    Jime, Jennifer A.
    Taylor, Sean D.
    Wrenn, Emma D.
    Waltner, Olivia
    Pfaltzgraff, Elise R.
    Song, Jane Y.
    Hall, Cody
    Wellik, Deneen M.
    Ljungman, Mats
    Furlan, Scott N.
    Ryan, Russell J. H.
    Sarthy, Jay F.
    Lawlor, Elizabeth R.
    CLINICAL CANCER RESEARCH, 2022, 28 (20) : 4466 - 4478
  • [2] Targeting the EWS–FLI1 transcription factor in Ewing sarcoma
    R. Tancredi
    A. Zambelli
    G. A. DaPrada
    V. Fregoni
    L. Pavesi
    A. Riccardi
    S. Burdach
    P. J. Grohar
    M. D’Incalci
    Cancer Chemotherapy and Pharmacology, 2015, 75 : 1317 - 1320
  • [3] Targeting EWS::FLI1 to Advance Ewing Sarcoma Therapy
    Mancarella, Caterina
    Scotlandi, Katia
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (31)
  • [4] Downstream EWS/FLI1 - upstream Ewing's sarcoma
    Heinrich Kovar
    Genome Medicine, 2
  • [5] A novel screening model to identify EWS::FLI1 regulators and their consequences on Ewing sarcoma plasticity
    Suresh, Veveeyan
    Fock, Valerie
    Schafer, Beat
    Kovar, Heinrich
    CANCER RESEARCH, 2023, 83 (07)
  • [6] EWS/FLI1 target genes and therapeutic opportunities in Ewing sarcoma
    Cidre-Aranaz, Florencia
    Alonso, Javier
    FRONTIERS IN ONCOLOGY, 2015, 5
  • [7] EWS/FLI1 regulates tumor anglogenesis in Ewing's sarcoma via suppression of thrombospondins
    Potikyan, Garv
    Savene, Rupert O. V.
    Gaulden, Julie M.
    France, Kelly A.
    Zhou, Zhichao
    Kleinerman, Eugenie S.
    Lessnick, Stephen L.
    Denny, Christopher T.
    CANCER RESEARCH, 2007, 67 (14) : 6675 - 6684
  • [8] EWS/FLI1 Hijacks UHRF1 to Drive the Malignancy of Ewing Sarcoma
    Xue, B.
    Feng, P.
    Shang, G.
    Xing, J.
    Li, X.
    Li, L.
    Zhao, J.
    Gong, H.
    Guan, H.
    Gassmann, H.
    Schober, S.
    Thiel, U.
    Burdach, S.
    Li, Y.
    PEDIATRIC BLOOD & CANCER, 2021, 68 : S146 - S147
  • [9] Efficacy of siRNA Nanocapsules Targeted Against the EWS–Fli1 Oncogene in Ewing Sarcoma
    Nedjma Toub
    Jean-Rémi Bertrand
    Ali Tamaddon
    Hind Elhamess
    Hervé Hillaireau
    Andrei Maksimenko
    Jean Maccario
    Claude Malvy
    Elias Fattal
    Patrick Couvreur
    Pharmaceutical Research, 2006, 23 : 892 - 900
  • [10] Role of Ewing sarcoma EWS/FLI1 protein in midzone formation during mitosis
    Azuma, Mizuki
    CANCER RESEARCH, 2017, 77