Life-threatening amlodipine and irbesartan poisoning in two adolescents: Extracorporeal life support is life-saving

被引：0

作者：

Koc, Gulizar ^{[1
]}

Ersayoglu, Irem ^{[1
]}

Cebeci, Kubra ^{[1
]}

Cinarli, Sercan ^{[2
]}

Ozkaya, Pinar Yazici ^{[1
]}

Tuncer, Osman Nuri ^{[3
]}

Karapinar, Bulent ^{[1
]}

机构：

[1] Ege Univ, Fac Med, Dept Pediat, Div Pediat Intens Care, Izmir, Turkiye

[2] Ege Univ, Fac Med, Dept Pediat, Izmir, Turkiye

[3] Ege Univ, Fac Med, Dept Cardiovasc Surg, Div Pediat Cardiovasc Surg, Izmir, Turkiye

来源：

TRENDS IN PEDIATRICS | 2024年 / 5卷 / 02期

关键词：

Amlodipine poisoning; irbesartan poisoning; vasoplegic shock; extracorporeal life support; children; MEMBRANE-OXYGENATION; MANAGEMENT;

D O I：

10.59213/TP.2024.134

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Calcium channel blockers (CCBs') and angiotensin receptor blockers (ARBs') are widely used in clinical practice and are easily available. Intoxication with these drugs results in life-threatening deep vasoplegic shock, making them particularly dangerous, especially for children. Here, we report two patients who ingested amlodipine and irbesartan for suicidal attempts and were unresponsive to all conventional treatments. They were placed on venoarterial extracorporeal membrane oxygenation (VA-ECMO) and hemodynamically stable immediately after extracorporeal life support (ECLS). Patients were successfully decannulated and extubated. CCB and ARB poisoning that are resistant to medical therapy can be treated by ECLS successfully.

引用

页码：48 / 51

页数：4

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