Sarcoidosis is a multisystemic disease characterized by the presence of non-caseating granulomas. We present a 26-year-old man who presents to the emergency department with fever, myalgia, excessive sweating, and weight loss. The analysis reveals pancytopenia, high than 150 U/L; splenomegaly, peri-aortic-caval retroperitoneal adenopathies confirmed by imaging. After ruling out the most common causes, a bronchoalveolar lavage showed an elevated CD4/CD8 ratio and lymphocytosis exceeding 50%, as well as confluent non-caseating epithelioid granulomas in the biopsy of the adenopathy, establishing the diagnosis of stage III sarcoidosis.
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Univ Sao Paulo, Fac Med FMUSP, Rheumatol Div, Av Dr Arnaldo 455,3 Andar Sala 3193, BR-01246903 Sao Paulo, SP, BrazilUniv Sao Paulo, Fac Med FMUSP, Rheumatol Div, Av Dr Arnaldo 455,3 Andar Sala 3193, BR-01246903 Sao Paulo, SP, Brazil
Macedo, Marina Bargui
Giardini, Henrique Ayres Mayrink
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Univ Sao Paulo, Fac Med FMUSP, Rheumatol Div, Av Dr Arnaldo 455,3 Andar Sala 3193, BR-01246903 Sao Paulo, SP, BrazilUniv Sao Paulo, Fac Med FMUSP, Rheumatol Div, Av Dr Arnaldo 455,3 Andar Sala 3193, BR-01246903 Sao Paulo, SP, Brazil
Giardini, Henrique Ayres Mayrink
Pereira, Rosa Maria Rodrigues
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Univ Sao Paulo, Fac Med FMUSP, Rheumatol Div, Av Dr Arnaldo 455,3 Andar Sala 3193, BR-01246903 Sao Paulo, SP, BrazilUniv Sao Paulo, Fac Med FMUSP, Rheumatol Div, Av Dr Arnaldo 455,3 Andar Sala 3193, BR-01246903 Sao Paulo, SP, Brazil
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Kings Coll London, Kings Business Sch, London, England
UNSW, Business Sch, Sch Mkt, Sydney, NSW, AustraliaKings Coll London, Kings Business Sch, London, England
de Ruyter, Ko
Keeling, Debbie Isobel
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Univ Sussex, Sch Business Management & Econ, Brighton, E Sussex, EnglandKings Coll London, Kings Business Sch, London, England
Keeling, Debbie Isobel
Liem Viet Ngo
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UNSW, Business Sch, Sch Mkt, Sydney, NSW, AustraliaKings Coll London, Kings Business Sch, London, England