Application of Pro-angiogenic Biomaterials in Myocardial Infarction

被引：0

作者：

Liang, Tingting ^{[1
]}

Liu, Jun ^{[1
]}

Liu, Feila ^{[1
]}

Su, Xiaohan ^{[2
]}

Li, Xue ^{[2
]}

Zeng, Jiao ^{[2
]}

Chen, Fuli ^{[3
,4
]}

Wen, Heling ^{[3
,4
]}

Chen, Yu ^{[3
,4
]}

Tao, Jianhong ^{[3
,4
]}

Lei, Qian ^{[5
]}

Li, Gang ^{[3
,4
]}

Cheng, Panke ^{[3
,4
,6
]}

机构：

[1] Chongqing Univ Technol, Sch Pharm & Bioengn, Chongqing 400050, Peoples R China

[2] North Sichuan Med Coll, Dept Breast & Thyroid Surg, Biol Targeting Lab Breast Canc, Acad Expert Workstat,Affiliated Hosp, Nanchong 637000, Peoples R China

[3] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Sch Med, Dept Cardiol, Chengdu 610054, Peoples R China

[4] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Inst Cardiovasc Dis, Sch Med, Chengdu 610054, Peoples R China

[5] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Sch Med, Dept Anesthesiol, Chengdu 610054, Peoples R China

[6] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Ultrasound Cardiac Electrophysiol & Biomech Key La, Chengdu 610054, Peoples R China

来源：

ACS OMEGA | 2024年 / 9卷 / 36期

基金：

中国国家自然科学基金;

关键词：

MESENCHYMAL STEM-CELLS; ENDOTHELIAL PROGENITOR CELLS; ISCHEMIA-REPERFUSION INJURY; FIBROBLAST-GROWTH-FACTOR; THERAPEUTIC ANGIOGENESIS; PROMOTES ANGIOGENESIS; CARDIAC-FUNCTION; EXTRACELLULAR VESICLES; CONDUCTIVE HYDROGELS; SIGNAL-TRANSDUCTION;

D O I：

10.1021/acsomega.4c04682

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biomaterials have potential applications in the treatment of myocardial infarction (MI). These biomaterials have the ability to mechanically support the ventricular wall and to modulate the inflammatory, metabolic, and local electrophysiological microenvironment. In addition, they can play an equally important role in promoting angiogenesis, which is the primary prerequisite for the treatment of MI. A variety of biomaterials are known to exert pro-angiogenic effects, but the pro-angiogenic mechanisms and functions of different biomaterials are complex and diverse, and have not yet been systematically described. This review will focus on the pro-angiogenesis of biomaterials and systematically describe the mechanisms and functions of different biomaterials in promoting angiogenesis in MI.

引用

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页码：37505 / 37529

页数：25

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