AI empowering traditional Chinese medicine?

被引:0
|
作者
Song, Zhilin [1 ,2 ]
Chen, Guanxing [3 ]
Chen, Calvin Yu-Chian [1 ,2 ,4 ,5 ,6 ]
机构
[1] Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, State Key Lab Chem Oncogen, Shenzhen 518055, Guangdong, Peoples R China
[2] Peking Univ, Sch Elect & Comp Engn, Shenzhen Grad Sch, AI Sci AI4S Preferred Program, Shenzhen 518055, Guangdong, Peoples R China
[3] Sun Yat Sen Univ, Artificial Intelligence Med Res Ctr, Sch Intelligent Syst Engn, Shenzhen Campus, Shenzhen 518107, Guangdong, Peoples R China
[4] China Med Univ Hosp, Dept Med Res, Taichung 40447, Taiwan
[5] Asia Univ, Dept Bioinformat & Med Engn, Taichung 41354, Taiwan
[6] Guangdong L Med Biotechnol Co Ltd, Meizhou 514699, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
NETWORK PHARMACOLOGY; HERBAL MEDICINE; SYNDROME DIFFERENTIATION; ARTIFICIAL-INTELLIGENCE; NATURAL-PRODUCTS; STRATEGY; TECHNOLOGY; DISCOVERY; DIAGNOSIS; EFFICACY;
D O I
10.1039/d4sc04107k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
For centuries, Traditional Chinese Medicine (TCM) has been a prominent treatment method in China, incorporating acupuncture, herbal remedies, massage, and dietary therapy to promote holistic health and healing. TCM has played a major role in drug discovery, with over 60% of small-molecule drugs approved by the FDA from 1981 to 2019 being derived from natural products. However, TCM modernization faces challenges such as data standardization and the complexity of TCM formulations. The establishment of comprehensive TCM databases has significantly improved the efficiency and accuracy of TCM research, enabling easier access to information on TCM ingredients and encouraging interdisciplinary collaborations. These databases have revolutionized TCM research, facilitating advancements in TCM modernization and patient care. In addition, advancements in AI algorithms and database data quality have accelerated progress in AI for TCM. The application of AI in TCM encompasses a wide range of areas, including herbal screening and new drug discovery, diagnostic and treatment principles, pharmacological mechanisms, network pharmacology, and the incorporation of innovative AI technologies. AI also has the potential to enable personalized medicine by identifying patterns and correlations in patient data, leading to more accurate diagnoses and tailored treatments. The potential benefits of AI for TCM are vast and diverse, promising continued progress and innovation in the field. AI-powered analysis of TCM chemical data enhances chemical component identification, drug discovery, personalized treatment, and pharmacological action elucidation, driving the modernization and sustainable development of TCM.
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页数:43
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