Comparison of Atherosclerotic Risk Factors and Hematologic Parameters Between Coronary Artery Ectasia and Obstructive Coronary Artery Disease

Objectives: This study aims to compare atherosclerosis risk factors between patients with coronary artery ectasia (CAE) and those with triple -vessel coronary artery disease (3VD). CAE is characterized by diffuse dilation in epicardial coronary arteries and is associated with risk factors for atherosclerosis. Methods: This retrospective cross-sectional study examined patients who underwent coronary angiography in our center between 2012 and 2016 and were diagnosed with CAE. Patients with 3VD served as the control group. Eligible patients ' medical records were reviewed, and relevant data, including demographic and clinical characteristics, atherosclerotic risk factors, and laboratory and inflammatory markers, were collected and documented. Results: The study population comprised 157 patients with CAE and 156 patients with 3VD. There was a significantly higher proportion of male patients in the 3VD group ( P <0.001). Smoking ( P <0.001), a history of acute coronary syndromes ( P <0.001), and dyslipidemia ( P <0.001) were significantly more prevalent in the 3VD group. The mean neutrophil-tolymphocyte ratio was significantly higher in the 3VD group than in the CAE group (3.6 +/- 3.0 vs 2.3 +/- 1.9; P <0.001). Conclusions: The findings of this study suggest that atherosclerosis risk factors and inflammatory markers may play a role in the development of CAE.