Cardiovascular diseases and the heart-gut cross talk

被引:1
|
作者
Majumder, Snehali [1 ]
Makwana, Rohan Kiritkumar [2 ]
Shetty, Varun [2 ]
Mukherjee, Suparna [3 ]
Narayan, Pradeep [2 ,4 ]
机构
[1] Narayana Hlth, Dept Clin Res, Bengaluru, India
[2] Narayana Hlth, Dept Cardiac Surg, Bengaluru, India
[3] Narayana Hlth, Dept Clin Res, Bengaluru, India
[4] Rabindranath Tagore Int Inst Cardiac Sci, 124 Mukundapur, Kolkata 700099, West Bengal, India
关键词
Metagenomics; Heart -gut axis; Cardiovascular diseases; Molecular pathways; MICROBIOME; METABOLISM;
D O I
10.1016/j.ihj.2023.12.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The purpose of this narrative review is to provide a comprehensive overview of current research on heart-gut cross talk and its implications for cardiovascular disease. To uncover relevant preclinical and clinical research examining heart-gut cross talk, a thorough literature search was undertaken utilising electronic databases. The chosen publications were critically examined, and major findings were synthesised to offer a thorough perspective on the subject. We want to synthesise the most recent study findings, explain the underlying mechanisms, and provide potential treatment techniques. By exploring bidirectional connection between the heart and the gut, we shed light on novel future options for the prevention and treatment of cardiovascular diseases. The heart-gut cross talk is an exciting field of study with implications for cardiovascular disease. Understanding the complex connection between the heart and the gastrointestinal tract may lead to the development of novel therapeutic targets and therapies for the prevention and management of cardiovascular diseases. Future research should concentrate on identifying the specific processes driving this crosstalk as well as assessing the efficacy of therapies targeting the gut microbiota and the gut-brain axis in improving cardiovascular outcomes.
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页码:94 / 100
页数:7
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