Regenerative mechanisms of stem cells and their clinical applications for degenerative eye diseases

被引：0

作者：

Zhang, Baodong ^{[1
]}

Gao, Shusong ^{[2
]}

Liu, Shibo ^{[1
]}

Gong, Xuewu ^{[3
]}

Wu, Jing ^{[3
]}

Zhang, Yu ^{[3
]}

Ma, Li ^{[3
]}

Sheng, Lijie ^{[3
]}

机构：

[1] Hulun Buir Aier Eye Hosp, Dept Ophthalmol, Hulunbuir, Inner Mongolia, Peoples R China

[2] Ezhou Cent Hosp, Dept Ophthalmol, Ezhou, Hubei, Peoples R China

[3] Qiqihar Med Univ, Affiliated Hosp 2, Dept Ophthalmol, Qiqihar 161006, Heilongjiang, Peoples R China

来源：

JOURNAL OF RESEARCH IN MEDICAL SCIENCES | 2024年 / 29卷 / 01期

关键词：

Eye diseases; mesenchymal stem cells; regeneration; stem cells; BONE-MARROW; PROGENITOR CELLS; STROMAL CELLS; PROMOTE ANGIOGENESIS; PERIPHERAL-BLOOD; EXPRESSION; TRANSPLANTATION; MIGRATION; THERAPY; GROWTH;

D O I：

10.4103/jrms.jrms_358_23

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There are different types of treatment for eye diseases. Although the majority of eye diseases are curable with primary treatments and surgery, some of degenerative eye damages need regeneration that is not gained by conventional procedures. Stem cells, such as mesenchymal stem cells, human embryonic stem cell-derived retinal pigmented epithelium, and inducible pluripotent stem cells, are now considered one of the most important and safe methods for regeneration of various damaged tissues or organs. However, how will stem cell therapy contribute to regeneration and overcome degenerative eye diseases? This review discusses the regenerative mechanisms, clinical applications, and advantages of different types of stem cells for restoring degenerative eye diseases.

引用

页数：12

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