Cow's milk allergy (CMA) is the most common food allergy in infants and young children. Allergic reactions may vary from mild to severe, such as an anaphylactic shock. In the case of a suspected CMA diagnosis, skin prick tests (SPT), immunoassays of specific IgE (sIgE) in blood serum (in vitro tests) and oral food challenge (OFC) tests can be performed. SPT wheal diameter and the level of serum specific IgE to milk do not correlate with the severity of clinical symptoms, and the OFC procedure is frequently difficult or even impossible in practice. Therefore, component -resolved diagnostic (CRD) tests are a new diagnostic tool, which allows a better correlation of laboratory test results with the observed clinical symptoms as well as identification of the triggering allergens.
机构:
Red Cross War Mem Childrens Hosp, Allergy Clin, Cape Town, South Africa
Christiaan Barnard Mem Hosp, Cape Town, South AfricaRed Cross War Mem Childrens Hosp, Allergy Clin, Cape Town, South Africa
Karabus, S. J.
du Tait, G.
论文数: 0|引用数: 0|
h-index: 0|
机构:
Kings Coll London, London WC2R 2LS, England
MRC, London W1N 4AL, England
Asthma UK Ctr Allerg Mechanisms Asthma, London, England
Guys & St Thomas NHS Fdn, Div Asthma Allergy & Lung Biol, London, EnglandRed Cross War Mem Childrens Hosp, Allergy Clin, Cape Town, South Africa