P2Y11 receptor is a critical regulator of extracellular ATP-mediated premature senescence in lung fibroblasts: Implications of ER-Ca+2 release/mitochondrial ROS production signaling pathway

被引：0
|
作者：
Shatat, Abdel-Aziz S. [1 ]
机构：
[1] Al Azhar Univ, Fac Pharm, Dept Pharmacol & Toxicol, El Nasr St, Nasr City 11751, Cairo, Egypt
来源：
PURINERGIC SIGNALLING | 2024年
关键词：
Premature senescence; Lung fibroblasts; Extracellular ATP; P2Y11; receptor; CELLULAR SENESCENCE; CANCER; ACTIVATION;
D O I：
10.1007/s11302-024-10036-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页数：3
相关论文
共 5 条
  • [1] ATP gradients inhibit the migratory capacity of specific human dendritic cell types:: implications for P2Y11 receptor signaling
    Schnurr, M
    Toy, T
    Stoitzner, P
    Cameron, P
    Shin, A
    Beecroft, T
    Davis, ID
    Cebon, J
    Maraskovsky, E
    BLOOD, 2003, 102 (02) : 613 - 620
  • [2] ATP-Evoked Intracellular Ca2+ Responses in M-CSF Differentiated Human Monocyte-Derived Macrophage are Mediated by P2X4 and P2Y11 Receptor Activation
    Layhadi, Janice A.
    Fountain, Samuel J.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (20)
  • [3] The P2Y11 receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses
    Dominik Klaver
    Hubert Gander
    Gabriele Dobler
    Andrea Rahm
    Martin Thurnher
    Cellular and Molecular Life Sciences, 2022, 79
  • [4] The P2Y11 receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses
    Klaver, Dominik
    Gander, Hubert
    Dobler, Gabriele
    Rahm, Andrea
    Thurnher, Martin
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2022, 79 (10)
  • [5] P2 X 7 receptor is a critical regulator of extracellular ATP-induced profibrotic genes expression in rat kidney: implication of transforming growth factor-β/Smad signaling pathway
    Mounieb, Fatma
    Abdel-Sattar, Somaia A.
    Balah, Amany
    Akool, El-Sayed
    PURINERGIC SIGNALLING, 2024, 20 (04) : 421 - 430
1