Exploring the Effects of Local Air Pollution on Popliteal Artery Aneurysms

被引:0
|
作者
Leinweber, Maria Elisabeth [1 ]
Meisenbacher, Katrin [2 ]
Schmandra, Thomas [3 ]
Karl, Thomas [4 ]
Torsello, Giovanni [5 ]
Walensi, Mikolaj [6 ]
Geisbuesch, Phillip [7 ]
Schmitz-Rixen, Thomas [8 ]
Jung, Georg [9 ]
Hofmann, Amun Georg [1 ]
机构
[1] FIFOS Forum Integrat Res & Syst Biol, A-1170 Vienna, Austria
[2] Univ Hosp Heidelberg, Dept Vasc & Endovasc Surg, D-69120 Heidelberg, Germany
[3] Sana Klinikum Offenbach, Dept Vasc Surg, D-63069 Offenbach, Germany
[4] SLK Kliniken Heilbronn GmbH, Dept Vasc & Endovasc Surg, Klinikum Plattenwald, D-74177 Bad Friedrichshall, Germany
[5] Franziskus Hosp Munster, Dept Vasc Surg, D-48145 Munster, Germany
[6] Contilia Heart & Vasc Ctr, Dept Vasc Surg & Phlebol, D-45138 Essen, Germany
[7] Klinikum Stuttgart, Dept Vasc & Endovasc Surg, D-70199 Stuttgart, Germany
[8] German Soc Surg, Langenbeck Virchow Haus,Luisenstr 58-59, D-10117 Berlin, Germany
[9] Luzerner Kantonsspital, Dept Vasc & Endovasc Surg, CH-6000 Lucern, Switzerland
关键词
popliteal artery aneurysm; air pollution; particulate matter; peripheral aneurysm; AMBIENT AIR; CARDIOVASCULAR-DISEASE; OXIDATIVE STRESS; EXPOSURE; INFLAMMATION; MARKERS; COAGULATION; DYSFUNCTION; MORTALITY; EVENTS;
D O I
10.3390/jcm13113250
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: A growing body of evidence highlights the effects of air pollution on chronic and acute cardiovascular diseases, such as associations between PM10 and several cardiovascular events. However, evidence of the impact of fine air pollutants on the development and progression of peripheral arterial aneurysms is not available. Methods: Data were obtained from the multicenter PAA outcome registry POPART and the German Environment Agency. Means of the mean daily concentration of PM10, PM2.5, NO2, and O3 concentrations were calculated for 2, 10, and 3650 days prior to surgery for each patient. Additionally, weighted ten-year averages were analyzed. Correlation was assessed by calculating Pearson correlation coefficients, and regression analyses were conducted as multiple linear or multiple logistic regression, depending on the dependent variable. Results: For 1193 patients from the POPART registry, paired air pollution data were available. Most patients were male (95.6%) and received open surgical repair (89.9%). On a regional level, the arithmetic means of the daily means of PM10 between 2000 and 2022 were neither associated with average diameters nor runoff vessels. Negative correlations for mean PAA diameter and mean NO2, as well as a positive correlation with mean O3, were found; however, they were not statistically significant. On patient level, no evidence for an association of mean PM10 exposure over ten years prior to inclusion in the registry and PAA diameter or the number of runoff vessels was found. Weighted PM10, NO2, and O3 exposure over ten years also did not result in significant associations with aneurysm diameter or runoff vessels. Short-term air pollutant concentrations were not associated with symptomatic PAAs or with perioperative complications. Conclusions: We found no indication that long-term air pollutant concentrations are associated with PAA size or severity, neither on a regional nor individual level. Additionally, short-term air pollution showed no association with clinical presentation or treatment outcomes.
引用
收藏
页数:11
相关论文
共 50 条
  • [1] ANEURYSMS OF THE POPLITEAL ARTERY
    TAKOLANDER, RJ
    BERGQVIST, D
    ERICSSON, BF
    JONSSON, K
    BERGENTZ, SE
    [J]. ACTA CHIRURGICA SCANDINAVICA, 1983, : 58 - 58
  • [2] Popliteal artery aneurysms
    Davidovic, LB
    Lotina, SI
    Kostic, DM
    Cinara, IS
    Cvetkovic, SD
    Markovic, DM
    Vojnovic, BR
    [J]. WORLD JOURNAL OF SURGERY, 1998, 22 (08) : 812 - 817
  • [3] ANEURYSMS OF THE POPLITEAL ARTERY
    TAKOLANDER, RJ
    BERGQVIST, D
    BERGENTZ, SE
    ERICSSON, BF
    SIGURJONSSON, S
    JONSSON, K
    [J]. ACTA CHIRURGICA SCANDINAVICA, 1984, 150 (02): : 135 - 140
  • [4] Popliteal Artery Aneurysms and Popliteal Phymas
    Hashimoto, Wataru
    Yamada, Takafumi
    Matsumaru, Ichiro
    [J]. ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY, 2009, 15 (01) : 64 - 67
  • [5] Popliteal Artery Aneurysms
    Lazar B. Davidovic
    Slobodan I. Lotina
    Dusan M. Kostic
    Ilijas S. Cinara
    Slobodan D. Cvetkovic
    Dragan M. Markovic
    Bojan R. Vojnovic
    [J]. World Journal of Surgery, 1998, 22 : 812 - 817
  • [6] ANEURYSMS OF POPLITEAL ARTERY
    HARDY, JD
    TOMPKINS, WC
    HATTEN, LE
    CHAVEZ, CM
    [J]. SURGERY GYNECOLOGY & OBSTETRICS, 1975, 140 (03): : 401 - 404
  • [7] 103 ANEURYSMS OF THE POPLITEAL ARTERY
    RIBAL, JP
    GLANDDIER, G
    [J]. LYON CHIRURGICAL, 1985, 81 (01) : 26 - 29
  • [8] Management of popliteal artery aneurysms
    Hamish, Maher
    Lockwood, Alistair
    Cosgrove, Christine
    Walker, Alasdair J.
    Wilkins, Denis
    Ashley, Simon
    [J]. ANZ JOURNAL OF SURGERY, 2006, 76 (10) : 912 - 915
  • [9] Ruptured popliteal artery aneurysms
    Akman, James
    Katsogridakis, Emmanuel
    Antoniou, George A.
    [J]. VASCULAR, 2019, 27 (04) : 430 - 447
  • [10] ARTERIOSCLEROTIC ANEURYSMS OF POPLITEAL ARTERY
    HUNTER, JA
    ORMAND, JC
    DYE, WS
    HUSHANG, J
    [J]. JOURNAL OF CARDIOVASCULAR SURGERY, 1961, 2 (05): : 404 - &