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- [8] Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation (vol 228, pg 105, 2008) TOXICOLOGY AND APPLIED PHARMACOLOGY, 2008, 231 (03) : 430 - 430