Optogenetic modulation of cardiac autonomic nervous system

被引:0
|
作者
Hernandez-Dominguez, Ramon A. [1 ,4 ]
Herrera-Orozco, Jorge F. [1 ]
Salazar-Calderon, Guadalupe E. [3 ]
Chavez-Canales, Maria [2 ]
Marquez, Manlio F. [1 ]
Gonzalez-Alvarez, Felipe [3 ]
Armando, Totomoch-Serra [1 ]
Reyes-Cruz, Tania [5 ]
Lip, Finn [3 ]
Aceves-Buendia, Jose J. [3 ]
机构
[1] Inst Nacl Cardiol Ignacio Chavez, Electrocardiol Dept, Juan Badiano Belisario Dominguez Secc 1, Mexico City 14080, Mexico
[2] Univ Nacl Autonoma Mexico, Unidad Invest UNAM INC, Ciudad Mex Inst Invest Biomed, Inst Nacl Cardiol Ignacio Chavez, Coyoacan 04510, Mexico
[3] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Neurol Dept, Vasco Quiroga 15 Belisario Dominguez,Secc 16, Mexico City 14080, Mexico
[4] Hosp Reg Alta Especial Dr Juan Graham Casasus, Surg Dept, Calle S-N,Miguel Hidalgo III Etapa, Tabasco 86126, Mexico
[5] Univ Autonoma Metropolitana, Microbiol Lab, Maestria Ciencias Farmaceut, Unidad Xochimilco, Calzada Hueso 1100 Villa Quietud Coyoacan, Mexico City 04960, Mexico
来源
关键词
Optogenetics; Autonomic nervous system; Sympathetic; Parasympathetic; Arrhythmias; SYMPATHETIC DENERVATION; MYOCARDIAL-INFARCTION; ATRIAL-FIBRILLATION; BLOOD-PRESSURE; VAGUS NERVE; HEART; STIMULATION; NEURONS; LOCALIZATION; ARRHYTHMIAS;
D O I
10.1016/j.autneu.2024.103199
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The following is a narrative review of the fundamentals of optogenetics. It focuses on the advantages and constraints of manipulating the autonomic nervous system by modifying the pathophysiological characteristics that arise in different diseases. Although the use of this technique is currently experimental, we will discuss improvements that have been implemented and identify the necessary measures for potential preclinical translation in the control of the cardiac autonomic nervous system.
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页数:10
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