Frailty and biological age. Which best describes our aging and longevity?

被引：1

作者：

Felix, Judith ^{[1
,3
]}

Martinez de Toda, Irene ^{[1
,3
]}

Diaz-Del Cerro, Estefania ^{[1
,3
]}

Gonzalez-Sanchez, Monica ^{[2
,3
]}

De la Fuente, Monica ^{[1
,3
]}

机构：

[1] Univ Complutense Madrid, Fac Biol Sci, Dept Genet Physiol & Microbiol, Unit Anim Physiol, Jose Antonio Novais 12, Madrid 28040, Spain

[2] Univ Complutense Madrid, Fac Biol Sci, Dept Genet Physiol & Microbiol, Unit Genet, Madrid 28040, Spain

[3] Inst Invest Hosp 12 Octubre Imas12, Madrid 28041, Spain

来源：

MOLECULAR ASPECTS OF MEDICINE | 2024年 / 98卷

关键词：

Frailty; Biological age; Aging; Longevity; Geriatrics; Gerontology; OLDER-ADULTS; SOCIAL FRAILTY; LEUKOCYTE FUNCTIONS; COGNITIVE FRAILTY; TELOMERE LENGTH; IMMUNE FUNCTION; ELDERLY-PEOPLE; EPIGENETIC AGE; LIFE; DEPRESSION;

D O I：

10.1016/j.mam.2024.101291

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Frailty and Biological Age are two closely related concepts; however, frailty is a multisystem geriatric syndrome that applies to elderly subjects, whereas biological age is a gerontologic way to describe the rate of aging of each individual, which can be used from the beginning of the aging process, in adulthood. If frailty reaches less consensus on the definition, it is a term much more widely used than this of biological age, which shows a clearer definition but is scarcely employed in social and medical fields. In this review, we suggest that this Biological Age is the best to describe how we are aging and determine our longevity, and several examples support our proposal.

引用

页数：12

共 8 条

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[7] Using a combination of chemical and systems biological approaches for defining a mechanism by which a novel anti-aging compound greatly extends yeast longevity
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