The emerging role of extracellular vesicles in bronchopulmonary dysplasia

被引:1
|
作者
Ransom, Meaghan A. [1 ]
Blatt, Alexander M. [2 ]
Pua, Heather H. [2 ,3 ,4 ]
Sucre, Jennifer M. S. [1 ,5 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Pediat, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN USA
[3] Vanderbilt Univ, Med Ctr, Vanderbilt Ctr Immunobiol, Nashville, TN USA
[4] Vanderbilt Univ, Med Ctr, Vanderbilt Inst Infect Immunol & Inflammat, Nashville, TN USA
[5] Vanderbilt Univ, Dept Cell & Dev Biol, Nashville, TN USA
基金
美国国家卫生研究院;
关键词
bronchopulmonary dysplasia; extracellular vesicles; ENDOTHELIAL GROWTH-FACTOR; DISEASE; MODEL;
D O I
10.1152/ajplung.00244.2023
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Extracellular vesicle (EV) biology in neonatal lung development and disease is a rapidly growing area of investigation. Although EV research in the neonatal population lags behind EV research in adult lung diseases, recent discoveries demonstrate promise in furthering our understanding of the pathophysiology of bronchopulmonary dysplasia and the potential use of EVs in the clinical setting, as both biomarkers and therapeutic agents. This review article explores some of the recent advances in this field and our evolving knowledge of the role of EVs in bronchopulmonary dysplasia.
引用
收藏
页码:L517 / L523
页数:7
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