What causes cough in pulmonary fibrosis, and how should we treat it?

被引:0
|
作者
Myall, Katherine J. [1 ,2 ]
Cho, Peter S. P. [1 ,2 ]
Birring, Surinder [1 ,2 ]
机构
[1] Kings Coll Hosp London, Dept Resp Med, Denmark Hill, London SE5 9RS, England
[2] Kings Coll London, London, England
关键词
chronic cough; cough hypersensitivity; interstitial lung disease; INTERSTITIAL LUNG-DISEASE; URGE-TO-COUGH; DOUBLE-BLIND; GASTROESOPHAGEAL-REFLUX; AIRWAY INFLAMMATION; PIRFENIDONE; MULTICENTER; SUPPRESSION; THERAPY;
D O I
10.1097/MCP.0000000000001087
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Purpose of reviewTo review the current understanding of the impact, mechanisms and treatments for cough in patients with interstitial lung disease (ILD). Evidence suggests that cough is a prevalent symptom in patients with ILD and has a significant impact on patients.Recent findingsThere is increasing interest in the role of cough hypersensitivity as seen in chronic refractory cough in patients with ILD, and encouraging recent results suggest that ILD-associated cough responds to opiate therapy.SummaryUnderstanding the aetiology of cough in patients with ILD is crucial to continue to develop therapies which might be effective in reducing cough and increasing quality of life.
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页码:523 / 529
页数:7
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