Food insecurity and COVID-19 vaccine hesitancy among adults in the United States (US)

Background: Some documented barriers of vaccination behaviors include social determinants of health (SDoH). While there have been many devastations from COVID-19, food security has fluctuated during the pandemic. The purpose of this study is to examine the association with food insecurity and vaccine hesitancy among adults in the U.S. Methods: In response to the COVID-19 pandemic, Federal agencies created the online Household Pulse Survey (HPS) to track social outcomes of the pandemic in the U.S. We performed cross-sectional analysis with data from the HPS collected between March 30, 2022, and April 11, 2022 (Week 44) on adults (N = 6449, weighted N = 37,687,910). Vaccine hesitancy was divided into two groups: 1) probably, not sure, probably not, and definitely not receiving the vaccine, and 2) received the vaccine and definitely will get the vaccine. Food sufficiency was a binary variable (Yes/no) based on the question that best described the food eaten in the household the last 7 days. Chi-square tests and multivariable logistic regressions were conducted using replicate weights with SAS. Logistic regressions adjusted for sex, age, race and ethnicity, income, education, COVID-19 infection, health insurance, food insecurity, children <17 years, remote work, health worker status, functional status, and mental health. Results: During HPS Week 44, 11.2 % of represented Americans experienced food insecurity and 13.8 % were vaccine hesitant. The unadjusted odds ratio was 2.41 (95 % CI = 1.30, 4.50), suggesting adults with food insecurity were more likely to be vaccine hesitant than those with food security. After adjusting for age, sex, race and ethnicity, marital status, and COVID-19 history, the statistical significance remained (AOR = 2.14, 95 % CI = 1.15, 3.99). However, after adjusting for education, we no longer observed a significant association (AOR = 1.70, 95 % CI = 0.89, 3.34), and it remained insignificant in the fully adjusted model (AOR = 1.62, 95 % CI = 0.78, 3.34). Conclusion: Overall, adults with food insecurity were 2.41 times as likely as those with food security to also have vaccine hesitancy. Education mediated the relationship between food insufficiency and vaccine hesitancy. Programs to improve vaccination rates need to also focus on food sufficiency.