Characterization of parotid gland tumors using diffusion-relaxation correlation spectrum imaging: a preliminary study

被引:1
|
作者
Chen, W. [1 ]
Geng, D. [1 ]
Xu, X. -Q. [1 ]
Hu, W. -T. [2 ]
Dai, Y. -M. [3 ]
Wu, F. -Y. [1 ]
Zhu, L. -N. [4 ]
机构
[1] Nanjing Med Univ, Dept Radiol, Affiliated Hosp 1, Nanjing, Peoples R China
[2] Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Dept Radiol, Shanghai, Peoples R China
[3] ShanghaiTech Univ, Sch Biomed Engn, Shanghai, Peoples R China
[4] Nanjing Med Univ, Dept Stomatol, Affiliated Hosp 1, Nanjing, Peoples R China
关键词
SIGNAL INTENSITY; WARTHIN TUMOR; CLASSIFICATION; NECK; HEAD; MRI;
D O I
10.1016/j.crad.2024.02.006
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
AIM: To assess the performance of diffusion -relaxation correlation spectrum imaging (DR -CSI) in the characterization of parotid gland tumors. MATERIALS AND METHODS: Twenty-five pleomorphic adenomas (PA) patients, 9 Warthin's tumors (WT) patients and 7 malignant tumors (MT) patients were prospectively recruited. DR-CSI (7 b-values combined with 5 TEs, totally 35 diffusion-weighted images) was scanned for pre-treatment assessment. Diffusion (D)-T2 signal spectrum summating all voxels were built for each patient, characterized by D-axis with range 0 similar to 5 x 10(-3) mm(2)/s, and T2-axis with range 0 similar to 300ms. With boundaries of 0.5 and 2.5 x 10(-3) mm(2)/s for D, all spectra were divided into three compartments labeled A (low D), B (mediate D) and C (high D). Volume fractions acquired from each compartment (V-A, V-B, V-C) were compared among PA, WT and MT. Diagnostic performance was assessed using receiver operating characteristic analysis and area under the curve (AUC). RESULTS: Each subtype of parotid tumors had their specific D-T2 spectrum. PA showed significantly lower V-A (8.85 +/- 4.77% vs 20.68 +/- 10.85%), higher V-B (63.40 +/- 8.18% vs 43.05 +/- 7.16%), and lower V-C (27.75 +/- 8.51% vs 36.27 +/- 11.09) than WT (all p<0.05). V-B showed optimal diagnostic performance (AUC 0.969, sensitivity 92.00%, specificity 100.00%). MT showed significantly higher V-A (21.23 +/- 12.36%), lower V-B (37.09 +/- 6.43%), and higher V-C (41.68 +/- 13.72%) than PA (all p<0.05). Similarly, V-B showed optimal diagnostic performance (AUC 0.994, sensitivity 96.00%, specificity 100.00%). No significant difference of V-A, V-B and V-C was found between WT and MT. CONCLUSIONS: DR -CSI might be a promising and non-invasive way for characterizing parotid gland tumors. (c) 2024 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:e878 / e884
页数:7
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