High intratumoral 5-hydroxymethylcytosine levels protect against disease relapse in patients with atypical fibroxanthoma and pleomorphic dermal sarcoma

被引：0

作者：

Gambichler, Thilo ^{[1
,2
,3
,4
]}

Razeghpour, Fahimeh ^{[1
]}

Sorescu, Emilia ^{[1
]}

Stuecker, Markus ^{[1
]}

Abu Rached, Nessr ^{[1
]}

Becker, Juergen C. ^{[5
,6
]}

Susok, Laura ^{[1
,3
,4
]}

机构：

[1] Ruhr Univ Bochum, Dept Dermatol, Bochum, Germany

[2] Christian Hosp Unna, Dept Dermatol, Unna, Germany

[3] Univ Witten Herdecke, Dortmund Hosp gGmbH, Dept Dermatol, Dortmund, Germany

[4] Univ Witten Herdecke, Fac Hlth, Dortmund, Germany

[5] Univ Duisburg Essen, West German Canc Ctr Dermatology, Translat Skin Canc Res, DKTK Partner Site Essen Dusseldorf, Essen, Germany

[6] German Canc Res Ctr, Heidelberg, Germany

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2024年 / 191卷 / 02期

关键词：

D O I：

10.1093/bjd/ljae171

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Hydroxymethylation plays a significant role in cancer development and progression. We hypothesized that hydroxymethylation markers may have prognostic potential in AFX/PDS (atypical fibroxanthoma/pleomorphic dermal sarcoma) as also observed in other tumours. Moreover, we wanted to find out whether hydroxymethylation markers might aid differentiation between AFX and PDS.

引用

页码：295 / 296

页数：2

共 8 条

[1] High intratumoral 5-Hydroxymethylcytosine Levels protect against Recurrence in Patients with atypical Fibroxanthoma and pleomorphic Sarcoma
Weyer-Fahlbusch, S. S.
Razeghpour, F.
Abu Rached, N.
Becker, J. C.
Susok, L.
Gambichler, T.
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2024, 22 : 7 - 7
[2] Atypical fibroxanthoma relapse as pleomorphic dermal sarcoma after slow Mohs micrographic surgery
Lopez-Llunell, Cristina
Yebenes, Mireia
Garbayo-Salmons, Patricia
Leal, Lorena
Mogedas-Vergara, Alfonso
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2021, 60 (10) : E424 - E427
[3] Risk of multiple primary cancers in patients with atypical fibroxanthoma/pleomorphic dermal sarcoma: A SEER analysis
Shah, Vraj K.
Nijhawan, Rajiv I.
JAAD INTERNATIONAL, 2024, 17 : 51 - 52
[4] Intratumoural programmed cell death protein expression in 92 patients with atypical fibroxanthoma and pleomorphic dermal sarcoma
Gambichler, Thilo
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Susok, Laura
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2024,
[5] The risk of subsequent skin cancer in patients with atypical fibroxanthoma or pleomorphic dermal sarcoma compared to the general population
van der Waa, Jose
van Midden, Dominique
Mellink, Jan Willem Albert
Flucke, Uta
Bonenkamp, Johannes Jozef
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JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2024, 91 (04) : 724 - 727
[6] Clinicopathological and Genomic Profiles of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma Identify Overlapping Signatures with a High Mutational Burden
Ak, Melike
Kahraman, Abdullah
Arnold, Fabian M.
Turko, Patrick
Levesque, Mitchell P.
Zoche, Martin
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GENES, 2021, 12 (07)
[7] Atypical fibroxanthoma and pleomorphic dermal sarcoma: Local recurrence and metastasis in a nationwide population-based cohort of 1118 patients
Orholt, Mathias
Abebe, Kiya
Rasmussen, Louise E.
Aaberg, Frederik L.
Lindskov, Laerke J.
Schmidt, Grethe
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[8] Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjogren's syndrome patients
Lagos, Carolina
Caryajal, Patricia
Castro, Isabel
Jara, Daniela
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Urzua, Ulises
Hermoso, Marcela A.
Leyton, Cecilia
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CLINICAL IMMUNOLOGY, 2018, 196 : 85 - 96

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