Ultrasound-Driven Highly Stable Implantable Triboelectric Nanogenerator with Human-Tissue Acoustic Impedance-Matched Polyether Ether Ketone

被引：1

作者：

Jeon, Sera ^{[1
]}

Meng, Xiangchun ^{[1
]}

Rubab, Najaf ^{[2
]}

Kim, Dabin ^{[3
]}

Mo, Hyeon ^{[1
]}

Xiao, Xiao ^{[1
]}

Park, Min Jae ^{[1
]}

Cho, Daniel Sanghyun ^{[3
]}

Kim, Seong Min ^{[1
]}

Choi, Byung-Ok ^{[4
]}

Kim, Sang-Woo ^{[1
]}

机构：

[1] Yonsei Univ, Ctr Human Oriented Triboelect Energy Harvesting, Dept Mat Sci & Engn, Seoul 03722, South Korea

[2] Gachon Univ, Dept Mat Sci & Engn, Seongnam 13120, South Korea

[3] Sungkyunkwan Univ SKKU, Sch Adv Mat Sci & Engn, Suwon 16419, South Korea

[4] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul 06351, South Korea

来源：

ADVANCED MATERIALS TECHNOLOGIES | 2024年 / 9卷 / 21期

基金：

新加坡国家研究基金会;

关键词：

acoustic impedance; implantable medical devices; nerve stimulation; polyether ether ketone; triboelectric nanogenerator; ELECTRONICS;

D O I：

10.1002/admt.202400317

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Implantable electrical neurostimulators offer a promising avenue for treating neurological disorders. However, their dependency on a finite battery life limits their long-term utility. Emerging transcutaneous ultrasound-driven triboelectric nanogenerator (TENG) techniques provide solutions for converting external ultrasound waves into internal electricity. This study proposes an implantable ultrasound-driven TENG (IU-TENG) using polyether ether ketone (PEEK) for its exceptional stability inside a human body and acoustic impedance compatibility with human tissues. This IU-TENG remarkably surpasses traditional titanium-based encapsulation, resulting in a 99.94% efficiency in ultrasound transmission. In addition, PEEK contains numerous electron-donating functional groups, making it suitable for TENG applications, particularly as a positive triboelectric layer. The device exhibits robust voltage outputs, reaching up to 11.50 and 8.75 V in water and in vivo, respectively, under body-safe ultrasound intensities. Moreover, its ability to sustain a stable electrical output for over 300 min emphasizes the durability and mechanical resilience of PEEK. In vivo mouse models and ex vivo porcine tissue trials demonstrate the effectiveness of the IU-TENG in nerve stimulation, showing its potential in medical treatments, enhancing the functionality and longevity of implantable medical devices. Implantable ultrasound-driven triboelectric nanogenerator (IU-TENG) is demonstrated, utilizing polyether ether ketone (PEEK) as an encapsulation and triboelectric layer for outstanding stability and tissue-matched acoustic impedance. This innovative IU-TENG achieves 99.94% efficiency in ultrasound transmission and sustains a stable electrical output for over 300 min under the safe ultrasound closure. This study provides comprehensive guidelines for high-efficiency, durable, and sustainable implantable medical devices. image

引用

页数：9