Perineural Injections of IncobotulinumtoxinA for Diabetic Neuropathic Pain of the Lower Extremities: Protocol for a Phase 2, Single-Center, Double-Blind, Randomized, Placebo-Controlled Trial (The PINBOT Study)

被引：0
|
作者：
Olsen, Marc Klee [1 ]
Thomsen, Trine Hormann [2 ]
Bitcsh, Martin Sabro [2 ]
Enggard, Thomas Peter [3 ]
Simonsen, Louise [2 ]
Jensen, Rigmor Hojland [4 ]
Biering-Sorensen, Bo [1 ]
机构：
[1] Rigshosp Glostrup, Neuropath Pain & CRPS Clin, Copenhagen, Denmark
[2] Bispebjerg Hosp, BDept Anaesthesiol, Copenhagen, Denmark
[3] Rigshosp, Multidisciplinary Pain Ctr, Copenhagen, Denmark
[4] Rigshosp Glostrup, Danish Headache Ctr, Copenhagen, Denmark
来源：
TOXICON | 2024年 / 237卷
关键词：
Clinical trial; Diabetic neuropathic pain; Perineural injections; IncobotulinumtoxinA; Efficacy; Safety;
D O I：
10.1016/j.toxicon.2024.107467
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：66 / 67
页数：2
相关论文
共 50 条
  • [1] Perineural injections of incobotulinumtoxin-A for diabetic neuropathic pain of the lower extremities: protocol for a phase II, single-centre, double-blind, randomised, placebo-controlled trial (the PINBOT study)
    Klee, Marc
    Thomsen, Trine Hormann
    Enggaard, Thomas Peter
    Bitsch, Martin Sabro
    Simonsen, Louise
    Jensen, Rigmor Hojland
    Biering-Sorensen, Bo
    BMJ OPEN, 2024, 14 (01):
  • [2] Efficacy of IncobotulinumtoxinA on Maskne: Evaluation in a Prospective, Single-Center, Placebo-Controlled, Double-Blind Study
    Kerscher, Martina
    Buntrock, Heike
    Gluecklich, Stefanie
    TOXICON, 2024, 237 : 39 - 39
  • [3] PLACEBO-CONTROLLED, RANDOMIZED, DOUBLE-BLIND STUDY OF INCOBOTULINUMTOXINA FOR SIALORRHEA
    Jost, W.
    Friedman, A.
    Michel, O.
    Oehlwein, C.
    Slawek, J.
    Bogucki, A.
    Ochudlo, S.
    Banach, M.
    Pagan, F.
    Flatau-Baque, B.
    Csikos, J.
    Cairney, C. J.
    Blitzer, A.
    PARKINSONISM & RELATED DISORDERS, 2023, 113 : 40 - 40
  • [4] A randomized, double-blind, placebo-controlled trial of a glycine antagonist in neuropathic pain
    Wallace, MS
    Rowbotham, MC
    Katz, NP
    Dworkin, RH
    Dotson, RM
    Galer, BS
    Rauck, RL
    Backonja, MM
    Quessy, SN
    Meisner, PD
    NEUROLOGY, 2002, 59 (11) : 1694 - 1700
  • [5] SIAXI Placebo-controlled, randomized, double-blind study of incobotulinumtoxinA for sialorrhea
    Jost, Wolfgang H.
    Friedman, Andrzej
    Michel, Olaf
    Oehlwein, Christian
    Slawek, Jaroslaw
    Bogucki, Andrzej
    Ochudlo, Stanislaw
    Banach, Marta
    Pagan, Fernando
    Flatau-Baque, Birgit
    Csikos, Janos
    Cairney, Claire J.
    Blitzer, Andrew
    NEUROLOGY, 2019, 92 (17) : E1982 - E1991
  • [6] Chinese Medicinal Formula (MHGWT) for Relieving Diabetic Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled Trial
    Tsai, Chia-I
    Li, Tsai-Chung
    Chang, Ming-Hong
    Lin, Shih-Yi
    Lee, I-Te
    Lee, Cheng-Hung
    Wang, Tzu-Yuan
    Su, Yi-Chang
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 2013
  • [7] Tolerability and Efficacy of Customized IncobotulinumtoxinA Injections for Essential Tremor: A Randomized, Double-Blind, Placebo-Controlled Study
    Jog, Mandar
    Lee, Jack
    Scheschonka, Astrid
    Chen, Robert
    Ismail, Farooq
    Boulias, Chris
    Hobson, Douglas
    King, David
    Althaus, Michael
    Simon, Olivier
    Dersch, Hanna
    Frucht, Steven
    Simpson, David M.
    TOXINS, 2020, 12 (12)
  • [8] Results of Mirogabalin Treatment for Diabetic Peripheral Neuropathic Pain in Asian Subjects: A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Study
    Baba, Masayuki
    Kuroha, Masanori
    Ohwada, Shoichi
    Murayama, Emiko
    Matsui, Norimitsu
    PAIN AND THERAPY, 2020, 9 (01) : 261 - 278
  • [9] Melatonin for Neuropathic Pain: Protocol for a Double-blind, Randomized Controlled Trial
    Gilron, Ian
    Tu, Dongsheng
    Holden, Ronald R.
    Moulin, Dwight E.
    Duggan, Scott
    Milev, Roumen
    JMIR RESEARCH PROTOCOLS, 2022, 11 (09):
  • [10] Mirogabalin for the treatment of diabetic peripheral neuropathic pain: A randomized, double-blind, placebo-controlled phase III study in Asian patients
    Baba, Masayuki
    Matsui, Norimitsu
    Kuroha, Masanori
    Wasaki, Yosuke
    Ohwada, Shoichi
    JOURNAL OF DIABETES INVESTIGATION, 2019, 10 (05) : 1299 - 1306
12345