The role of metabolic reprogramming in kidney cancer

被引:0
|
作者
Chen, Ziyi [1 ]
Zhang, Xiaohong [2 ,3 ,4 ]
机构
[1] Fujian Med Univ, Clin Med Coll 1, Fuzhou, Peoples R China
[2] Fujian Med Univ, Affiliated Hosp 1, Blood Purificat Res Ctr, Dept Nephrol, Fuzhou, Peoples R China
[3] Fujian Med Univ, Affiliated Hosp 1, Fujian Clin Res Ctr Metab Chron Kidney Dis, Fuzhou, Peoples R China
[4] Fujian Med Univ, Affiliated Hosp 1, Natl Reg Med Ctr, Dept Nephrol, Binhai Campus, Fuzhou, Peoples R China
来源
FRONTIERS IN ONCOLOGY | 2024年 / 14卷
关键词
metabolism reprogramming; renal cancer; treatment; glucose metabolism; amino acid metabolism; RENAL-CELL CARCINOMA; GROWTH; MYC; PROLIFERATION; HOMEOSTASIS; EXPRESSION; INHIBITORS; ADENOSINE; PATHWAY; BENEFIT;
D O I
10.3389/fonc.2024.1402351
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Metabolic reprogramming is a cellular process in which cells modify their metabolic patterns to meet energy requirements, promote proliferation, and enhance resistance to external stressors. This process also introduces new functionalities to the cells. The 'Warburg effect' is a well-studied example of metabolic reprogramming observed during tumorigenesis. Recent studies have shown that kidney cells undergo various forms of metabolic reprogramming following injury. Moreover, metabolic reprogramming plays a crucial role in the progression, prognosis, and treatment of kidney cancer. This review offers a comprehensive examination of renal cancer, metabolic reprogramming, and its implications in kidney cancer. It also discusses recent advancements in the diagnosis and treatment of renal cancer.
引用
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页数:9
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