Exploring Prescription Practices: Insights from an Antimicrobial Stewardship Program at a Tertiary Healthcare Facility, Rwanda

被引:0
|
作者
Gashegu, Misbah [1 ]
Gahamanyi, Noel [1 ,2 ]
Ndayambaje, Francois Xavier [3 ]
Munyemana, Jean Bosco [3 ]
Ndahindwa, Vedaste [4 ]
Lukwago, Fredrick [5 ]
Ingabire, Lambert [5 ]
Gambanga, Fiona [6 ]
Gashema, Pierre [7 ,8 ]
Tuyishime, Albert [1 ]
Dzinamarira, Tafadzwa [9 ]
Dukundane, Damas [5 ]
Muvunyi, Thierry Zawadi [5 ]
Muvunyi, Claude Mambo [1 ,4 ]
机构
[1] Rwanda Biomed Ctr, POB 7162, Kigali, Rwanda
[2] Univ Rwanda, Coll Sci & Technol, Biol Dept, POB 3900, Kigali, Rwanda
[3] Univ Rwanda, Coll Med & Hlth Sci, Sch Med, Dept Microbiol & Parasitol, POB 3286, Kigali, Rwanda
[4] Univ Rwanda, Sch Publ Hlth, Coll Med & Hlth Sci, POB 3286, Kigali, Rwanda
[5] King Faisal Hosp, POB 2534, Kigali, Rwanda
[6] Clinton Hlth Access Initiat, POB 4062, Kigali, Rwanda
[7] Repolicy Res Ctr, POB 7584, Kigali, Rwanda
[8] Univ Edinburgh, Coll Med & Vet Med, Edinburgh EH8 9YL, Scotland
[9] ICAP, Int Ctr AIDS Care & Treatment Program, Lusaka 34358, Zambia
来源
ANTIBIOTICS-BASEL | 2024年 / 13卷 / 06期
关键词
antimicrobial resistance; antibiotic prescription; healthcare providers; infection prevention; Rwanda; ANTIBIOTICS; RESISTANCE;
D O I
10.3390/antibiotics13060548
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Antimicrobial resistance (AMR) is a major public health threat linked to increased morbidity and mortality. It has the potential to return us to the pre-antibiotic era. Antimicrobial stewardship (AMS) programs are recognized as a key intervention to improve antimicrobial use and combat AMR. However, implementation of AMS remains limited in Africa, particularly in Rwanda. This study aimed to assess prescription practices, identify areas for improvement, and promote adherence to AMS principles. Conducted at King Faisal Hospital in Rwanda, this qualitative study used semi-structured interviews with eight participants until saturation was reached. The interviews were recorded, transcribed, and thematically analyzed, revealing four emerging themes. The first theme was on AMS activities that were working well based on availability of microbiology laboratory results and prescription guidelines as factors influencing antibiotic prescription adjustments. The second theme was related to challenges during the implementation of the AMS program, including the prescription of broad-spectrum antibiotics, limited local data on AMR patterns, and stock-outs of essential antibiotics. The third theme was on the importance of adhering to AMR management guidelines at KFH. The last emerged on recommendations from participants centered on regular training for healthcare workers, widespread dissemination of AMR findings across departments, and the enforcement of antibiotic restriction policies. These actions can improve prescription behaviors, upholding the highest standards of patient care, and strengthening the nascent AMS program.
引用
收藏
页数:12
相关论文
共 50 条
  • [1] Point Prevalence Survey of Antimicrobial Prescription and Consumption in a Nigerian Tertiary Hospital: A Gateway to the Antimicrobial Stewardship Program
    Nwafia, I. N.
    Nwachukwu, P. T.
    Orakwe, O.
    Ebede, S. O.
    Amagwu, C.
    Aroh, A.
    Orabueze, O.
    Ndubueze, C.
    Okeke, P.
    Ijere, O.
    Izundu, D.
    Ohanu, M.
    Ozumba, U.
    Oduyebo, O.
    Versporten, A.
    [J]. NIGERIAN JOURNAL OF CLINICAL PRACTICE, 2024, 27 (06) : 702 - 707
  • [2] High Prevalence of Antimicrobial Resistance Among Common Bacterial Isolates in a Tertiary Healthcare Facility in Rwanda
    Ntirenganya, Cyprien
    Manzi, Olivier
    Muvunyi, Claude Mambo
    Ogbuagu, Onyema
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2015, 92 (04): : 865 - 870
  • [3] Antimicrobial stewardship program directed at broad-spectrum intravenous antibiotics prescription in a tertiary hospital
    V. C. C. Cheng
    K. K. W. To
    I. W. S. Li
    B. S. F. Tang
    J. F. W. Chan
    S. Kwan
    R. Mak
    J. Tai
    P. Ching
    P. L. Ho
    W. H. Seto
    [J]. European Journal of Clinical Microbiology & Infectious Diseases, 2009, 28 : 1447 - 1456
  • [4] Antimicrobial stewardship program directed at broad-spectrum intravenous antibiotics prescription in a tertiary hospital
    Cheng, V. C. C.
    To, K. K. W.
    Li, I. W. S.
    Tang, B. S. F.
    Chan, J. F. W.
    Kwan, S.
    Mak, R.
    Tai, J.
    Ching, P.
    Ho, P. L.
    Seto, W. H.
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2009, 28 (12) : 1447 - 1456
  • [5] The Norton Healthcare electronic antimicrobial stewardship program: An opt-out approach to antimicrobial stewardship
    Wilde, Ashley M.
    Song, Matthew
    Moore, Sarah E.
    Bohn, Brian C.
    Swingler, Elena
    Schulz, Paul M.
    [J]. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2023, 80 (02) : 75 - 82
  • [6] Development of an antimicrobial stewardship program in an integrated healthcare system
    Lane, Michael A.
    Hays, Amanda J.
    Newland, Helen
    Zack, Jeanne E.
    Guth, Rebecca M.
    Newland, Jason G.
    [J]. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2019, 76 (01) : 34 - 43
  • [7] Point Prevalence Survey of Antimicrobial Prescription and Consumption in a Nigerian Tertiary Hospital: A Gateway to the Antimicrobial Stewardship Program (vol 27, 702, 2024)
    Nwafia, I. N.
    Nwachukwu, P. T.
    Orakwe, O.
    Ebede, S. O.
    Amagwu, C.
    Aroh, A.
    Orabueze, I. N.
    Ndubueze, C.
    Okeke, P.
    Ijere, O.
    Izundu, D.
    Ohanu, M.
    Ozumba, U.
    Oduyebo, O.
    Versporten, A.
    [J]. NIGERIAN JOURNAL OF CLINICAL PRACTICE, 2024, 27 (09) : 1120 - 1120
  • [8] Antimicrobial stewardship program for gastrointestinal surgeries at a Vietnamese tertiary hospital
    Pham, Hong Tham
    Mai-Phan, Tuong-Anh
    Nguyen, Anh Dung
    Nguyen, Van-Quang-Huy
    Tran, Minh-Hoang
    [J]. FRONTIERS IN MEDICINE, 2024, 11
  • [9] Antimicrobial Prescription Errors in Hospitalized Children: Role of Antimicrobial Stewardship Program in Detection and Intervention
    Di Pentima, M. Cecilia
    Chan, Shannon
    Eppes, Stephen C.
    Klein, Joel D.
    [J]. CLINICAL PEDIATRICS, 2009, 48 (05) : 505 - 512
  • [10] Impact of an Antimicrobial Stewardship Program on Unnecessary Double Anaerobic Coverage Prescription
    Song, Young Joo
    Kim, Moonsuk
    Huh, Saemi
    Lee, Junghwa
    Lee, Eunsook
    Song, Kyoung-Ho
    Kim, Eu Suk
    Kim, Hong Bin
    [J]. INFECTION AND CHEMOTHERAPY, 2015, 47 (02): : 111 - 116