The impact of a physical exercise program on quality of life, fatigue, physical performance, and level of physical activity in patients with cancer

Objective: Increasing evidence suggests that exercise programs are of great value in the rehabilitation and survivorship of patients with cancer. However, challenges remain regarding maintaining patients more physically active. This study aimed to evaluate the impact of a supervised exercise program on quality of life, fatigue, physical performance, and levels of physical activity of patients with cancer. Methods: An observational longitudinal study, with a 1-year prospective follow-up, was developed. Setting: This is a university-based outpatient rehabilitation program in a high-complexity cancer care center in Sao Paulo. Results: After the program, patients showed a significant gain in quality of life (p<0.0001), physical performance (p<0.0001), and improvement in fatigue (p<0.0001). After 12 months, 81.1% of the patients remained active, and only 4.5% declared themselves to be sedentary. Conclusion: The results of this study confirm that exercise programs are an important tool in the rehabilitation of patients with cancer and that an initial supervised exercise program, in combination with follow-ups, can help increase the levels of physical activity of this population.