Sunlight: Time for a Rethink?

被引:1
|
作者
Weller, Richard B. [1 ,2 ]
机构
[1] Univ Edinburgh, Inst Regenerat & Repair, Ctr Inflammat Res, Edinburgh, Scotland
[2] Univ Edinburgh, Dept Dermatol, Lauriston Bldg,Lauriston Pl, Edinburgh EH3 9HA, Scotland
关键词
Environment and public health; Health status; Mortality; Nitric oxide; UVR; VITAMIN-D SUPPLEMENTATION; NITRIC-OXIDE; CARDIOVASCULAR-DISEASE; 25-HYDROXYVITAMIN D; SEASONAL-VARIATION; BLOOD-PRESSURE; UROCANIC ACID; SUN EXPOSURE; RISK-FACTOR; EAST-ASIA;
D O I
10.1016/j.jid.2023.12.027
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
UVR is a skin carcinogen, yet no studies link sun exposure to increased all-cause mortality. Epidemiological studies from the United Kingdom and Sweden link sun exposure with reduced all-cause, cardiovascular, and cancer mortality. Vitamin D synthesis is dependent on UVB exposure. Individuals with higher serum levels of vitamin D are healthier in many ways, yet multiple trials of oral vitamin D supplementation show little benefit. Growing evidence shows that sunlight has health benefits through vitamin D-independent pathways, such as photomobilization of nitric oxide from cutaneous stores with reduction in cardiovascular morbidity. Sunlight has important systemic health benefit as well as risks.
引用
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页码:1724 / 1732
页数:9
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