iPSC-BASED IMMUNOTHERAPY DIFFERENTIATION PLATFORM ENABLES FEEDER-FREE EXPANSION OF NK CELLS TO CLINICAL SCALE

被引：0
|
作者：
Terheyden-Keighley, D. [1 ]
Hiller, B. [1 ]
Gamerschlag, A. [1 ]
Greber, B. [1 ]
机构：
[1] Catalent Dusseldorf, R&D, Langenfeld, Germany
来源：
CYTOTHERAPY | 2024年 / 26卷 / 06期
关键词：
NK; feeder; -free; expansion;
D O I：
暂无
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
1008
引用
收藏
页码：S198 / S199
页数：2
相关论文
共 15 条
  • [1] CLINICAL-SCALE NON-VIRAL BASED ENGINEERING AND FEEDER-FREE PRODUCTION OF CAR-NK CELLS FOR CANCER IMMUNOTHERAPY
    Kumar, D.
    Liu, A.
    Heipertz, E.
    Ravinder, N.
    CYTOTHERAPY, 2024, 26 (06) : S178 - S178
  • [2] Expansion of human peripheral blood NK cells in serum- and feeder-free culture
    Le Fevre, Tim A.
    Ang, Elaine
    Wognum, Albertus W.
    Szilvassy, Stephen J.
    Eaves, Allen C.
    Louis, Sharon A.
    Zavareh, Nooshin Tabatabaei
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2021, 51 : 132 - 132
  • [3] Serum- and feeder-free culture expansion of human peripheral blood NK cells
    Le Fevre, Tim
    Ang, Elaine
    Wognum, Albertus W.
    Szilvassy, Stephen J.
    Louis, Sharon A.
    Eaves, Allen C.
    Tabatabaei-Zavareh, Nooshin
    JOURNAL OF IMMUNOLOGY, 2021, 206
  • [4] Advancing Cancer Immunotherapy: Large-Scale Non-Viral Engineering and Feeder-Free Production of CAR-NK Cells
    Kumar, Deepak
    Liu, Anna
    Heipertz, Erica
    Ravinder, Namritha
    MOLECULAR THERAPY, 2024, 32 (04) : 635 - 636
  • [5] Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor
    Sutlu, Tolga
    Stellan, Birgitta
    Gilljam, Mari
    Quezada, Hernan Concha
    Nahi, Hareth
    Gahrton, Gosta
    Alici, Evren
    CYTOTHERAPY, 2010, 12 (08) : 1044 - 1055
  • [6] Generation of functional cardiomyocytes from rat embryonic and induced pluripotent stem cells using feeder-free expansion and differentiation in suspension culture
    Dahlmann, Julia
    Awad, George
    Dolny, Carsten
    Weinert, Soenke
    Richter, Karin
    Fischer, Klaus-Dieter
    Munsch, Thomas
    Lessmann, Volkmar
    Volleth, Marianne
    Zenker, Martin
    Chen, Yaoyao
    Merkl, Claudia
    Schnieke, Angelika
    Baraki, Hassina
    Kutschka, Ingo
    Kensah, George
    PLOS ONE, 2018, 13 (03):
  • [7] Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture
    Li, Yan-Ruide
    Zhou, Kuangyi
    Lee, Derek
    Zhu, Yichen
    Halladay, Tyler
    Yu, Jiaji
    Zhou, Yang
    Lyu, Zibai
    Fang, Ying
    Chen, Yuning
    Semaan, Sasha
    Yang, Lili
    NATURE PROTOCOLS, 2025,
  • [8] A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cells
    Lu, Hong Fang
    Chai, Chou
    Lim, Tze Chiun
    Leong, Meng Fatt
    Lim, Jia Kai
    Gao, Shujun
    Lim, Kah Leong
    Wan, Andrew C. A.
    BIOMATERIALS, 2014, 35 (09) : 2816 - 2826
  • [9] Rock Inhibitor Y-27632 Enables Feeder-Free, Unlimited Expansion of Sus scrofa domesticus Swine Airway Stem Cells to Facilitate Respiratory Research
    Dale, Tina P.
    Borg D'anastasi, Emily
    Haris, Mohammed
    Forsyth, Nicholas R.
    STEM CELLS INTERNATIONAL, 2019, 2019
  • [10] Improved Expansion Of Primary Human Airway Epithelial Cells Using A Novel Defined And Feeder-Free Medium That Promotes Maintenance Of Their Mucociliary Differentiation Potential In Later Passages
    Hou, J.
    Brown, T.
    Riedel, M. J.
    Thomas, T. E.
    Eaves, A. C.
    Louis, S. A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
12