Interproximal reduction in the refinement phase of Invisalign treatment: A quantitative analysis

Introduction: Interproximal reduction (IPR) is a common adjunct to contemporary orthodontic treatment. This study aimed to carry out a quantitative analysis of IPR prescribed in the refinement phases of clear aligner therapy with the Invisalign appliance (Align Technology, San Jose, Calif). Methods: The digital treatment plans (DTPs) of a total of 330 patients treated by 11 orthodontists were evaluated. Relevant data regarding patient age, gender, and prescription of IPR in the initial and refined DTPs were obtained from Align Technology's digital interface, ClinCheck. Computational analyses included descriptive statistics, Mann-Whitney U, and KruskalWallis tests. Results: Most (n = 182; 75.2%) of the 242 patients who satisfied inclusion criteria were females. The median (interquartile range [IQR]) age was 29.2 (22.1-40.2) years. More than 60% of the contact sites prescribed IPR related to the initial DTP (n = 1312; 60.4%), with 39.6% (n = 859) recorded in the refinement DTPs. A median (IQR) of 1.1 (0.6-2.1) mm of IPR was prescribed per patient in the initial DTP compared with a median (IQR) of 0.6 (0.3-1.3) mm in the refinement DTPs. The most common site for prescribed IPR in all DTPs was the mandibular anterior region. Almost half (n = 108; 44.6%) of the patients were prescribed IPR at the same contact point site more than once during treatment. Conclusions: Almost 40% of the contact points that were prescribed IPR were in the patients' refinement DTPs. Most IPR was prescribed for the anterior region of the mandible. Almost half of the patients had IPR repeatedly prescribed at the same sites during treatment. (Am J Orthod Dentofacial Orthop 2024;165:689-96)