Efficacy of Aloe Vera, Amlexanox (5%), and Triamcinolone Acetonide (0.1%) in the Management of Oral Lichen Planus

被引：0
|
作者：
Kaur, Manpreet [1 ]
Gulati, Prerna [2 ]
Verma, Sugandha [3 ]
Khare, Parul [4 ]
Garg, Ruchi [5 ]
Dutta, Jahnobi [6 ]
Rao, Kumuda [7 ]
机构：
[1] Maharishi Markandeshwar Coll Dent Sci & Res, Dept Oral Pathol, Mullana, Haryana, India
[2] Guru Nanak Dev Dent Coll & Res Inst, Dept Publ Hlth Dent, Sunam, Punjab, India
[3] Rajendra Inst Med Sci, Dept Oral Med & Radiol, Dent Coll, Ranchi, Bihar, India
[4] Sharda Univ, Sch Dent Sci, Dept Oral & Maxillofacial Pathol & Oral Microbiol, Greater Noida, India
[5] Swami Devi Dyal Hosp & Dent Coll, Dept Publ Hlth Dent, Panchkula, Haryana, India
[6] Govt Dent Coll, Dept Oral & Maxillofacial Pathol, Dibrugarh, Assam, India
[7] Nitte, AB Shetty Mem Inst Dent Sci, Dept Oral Med & Radiol, Mangalore, Karnataka, India
来源：
JOURNAL OF PHARMACY AND BIOALLIED SCIENCES | 2024年 / 16卷
关键词：
Aloe vera; erosive; mucosa; oral lichen planus; visual analogue scale;
D O I：
10.4103/jpbs.jpbs_416_23
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Objective: This research assessed the efficiencies of aloe vera, 0.1% triamcinolone acetonide, and 5% amlexanox in the management of OLP. Materials and Methods: A total of 120 participants diagnosed with oral lichen planus (OLP) were equally divided into three groups and treated with: aloe vera, (Group A), 0.1% triamcinolone acetonide (Group B), and 5% amlexanox (Group C) topical medicaments. The patients were evaluated for pain, using the visual analogue scale (VAS). They were also evaluated for ulcerative lesion type and erosive area on days 1, 7, and 15 of the study. Results: There was a statistically considerable decrease in the VAS pain scale score, reduction in the erosive area on buccal mucosa, and healing of ulcer from day 1st to 15th day with all three tested drugs. Conclusion: All drugs used in this study; aloe vera, triamcinolone acetonide, and amlexanox were effective in treating OLP patients.
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收藏
页码：S133 / S135
页数：3
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