Formulation, evaluation and bioequivalence studies of apixaban tablet

This research showed how to prepare and assess immediate release doses of apixaban. In this research study, we are formulating apixaban by wet granulation method. Prior studies have been carried out using direct compression and dry granulation techniques.The proposed wet granulation method has several advantages in terms of feasibility and cost effectiveness. The current formulation compares the performance of disintegrants such croscarmellose sodium (CCS) and sodium starch glycolate (SSG), with the latter being proven to produce the best outcomes. Superdisintegrants are compounds that, as their name implies, are superior to disintegrants and that facilitate or enhance the dissolution time steady at minimal levels, usually 1-10% by weight virtual to the total mass of the amount item. These are used to boost the potency of the solid dosage form.