Targeting excitatory:inhibitory network imbalance in Alzheimer's disease

被引:0
|
作者
Blum, David [1 ,2 ]
Levi, Sabine [3 ,4 ]
机构
[1] Univ Lille, Inserm, CHU Lille, UMR S1172,Lille Neurosci & Cognit LilNCog, F-59000 Lille, France
[2] LabEx DISTALZ, Alzheimer & Tauopathies, F-59000 Lille, France
[3] Sorbonne Univ, Inst Fer Moulin, Inserm UMR S 1270, F-75005 Paris, France
[4] PSL Res Univ, Brain Plast Lab, CNRS, ESPCI Paris, F-75005 Paris, France
关键词
D O I
10.1093/brain/awae146
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This scientific commentary refers to 'Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer's disease and 5XFAD mice' by Barbour et al. (https://doi.org/10.1093/brain/awae126). © 2024 The Author(s).
引用
收藏
页码:1931 / 1933
页数:3
相关论文
共 50 条
  • [1] Excitatory-inhibitory imbalance in Alzheimer's disease and therapeutic significance
    Varela, Eva Vico
    Etter, Guillaume
    Williams, Sylvain
    NEUROBIOLOGY OF DISEASE, 2019, 127 : 605 - 615
  • [2] Seizures Exacerbate Cognitive Deficits and Excitatory: Inhibitory Imbalance in Alzheimer's Disease
    Barbour, Aaron
    ANNALS OF NEUROLOGY, 2023, 94 : S205 - S205
  • [3] GABAergic dysfunction in excitatory and inhibitory (E/I) imbalance drives the pathogenesis of Alzheimer's disease
    Bi, Danlei
    Wen, Lang
    Wu, Zujun
    Shen, Yong
    ALZHEIMERS & DEMENTIA, 2020, 16 (09) : 1312 - 1329
  • [4] Global Electrophysiological Excitatory to Inhibitory Imbalance in Hippocampus and Temporal Cortex in the Continuum of Alzheimer's Disease
    Scaduto, Pietro
    Russell, William
    Limon, Agenor
    NEUROPSYCHOPHARMACOLOGY, 2022, 47 (SUPPL 1) : 299 - 300
  • [5] Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer's disease and 5XFAD mice
    Barbour, Aaron J.
    Gourmaud, Sarah
    Lancaster, Eunjoo
    Li, Xiaofan
    Stewart, David A.
    Hoag, Keegan F.
    Irwin, David J.
    Talos, Delia M.
    Jensen, Frances E.
    BRAIN, 2024, 147 (06) : 2169 - 2184
  • [6] Global Electrophysiological Excitatory to Inhibitory Imbalance in Hippocampus and Temporal Cortex in the Continuum of Alzheimer's Disease
    Scaduto, Pietro
    Russell, William
    Limon, Agenor
    NEUROPSYCHOPHARMACOLOGY, 2022, 47 : 299 - 300
  • [7] Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer's disease neuropathologic change
    Scaduto, Pietro
    Lauterborn, Julie C.
    Cox, Conor D.
    Fracassi, Anna
    Zeppillo, Tommaso
    Gutierrez, Berenice A.
    Keene, C. Dirk
    Crane, Paul K.
    Mukherjee, Shubhabrata
    Russell, William K.
    Taglialatela, Giulio
    Limon, Agenor
    ACTA NEUROPATHOLOGICA, 2023, 145 (03) : 303 - 324
  • [8] Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer’s disease neuropathologic change
    Pietro Scaduto
    Julie C. Lauterborn
    Conor D. Cox
    Anna Fracassi
    Tommaso Zeppillo
    Berenice A. Gutierrez
    C. Dirk Keene
    Paul K. Crane
    Shubhabrata Mukherjee
    William K. Russell
    Giulio Taglialatela
    Agenor Limon
    Acta Neuropathologica, 2023, 145 : 303 - 324
  • [9] A Reliable Measure of Excitatory / Inhibitory (E/I) Balance in Alzheimer's Disease
    Molina, Juan
    Sprock, Joyce
    Iwanaga, Dylan
    Talledo, Jo
    Joshi, Yash
    Voytek, Bradley
    Delano-Wood, Lisa
    Gonzalez, Christopher
    Huege, Steven
    Leger, Gabriel
    Light, Greg
    Swerdlow, Neal
    NEUROPSYCHOPHARMACOLOGY, 2022, 47 : 291 - 291
  • [10] A Reliable Measure of Excitatory / Inhibitory (E/I) Balance in Alzheimer's Disease
    Molina, Juan
    Sprock, Joyce
    Iwanaga, Dylan
    Talledo, Jo
    Joshi, Yash
    Voytek, Bradley
    Delano-Wood, Lisa
    Gonzalez, Christopher
    Huege, Steven
    Leger, Gabriel
    Light, Greg
    Swerdlow, Neal
    NEUROPSYCHOPHARMACOLOGY, 2022, 47 (SUPPL 1) : 291 - 291