Primary Lung Squamous Cell Carcinoma With Intestinal Metastasis: A Case Report and Literature Review

Lung squamous cell carcinoma (LUSC) is characterized by a high rate of metastasis and recurrence, leading to a poor prognosis for affected patients. Intestinal metastasis of LUSC is a rare clinical occurrence. Treatment options for LUSC patients with intestinal metastasis are limited, and no standard therapy guidelines exist for managing these cases. In this review, we discuss the clinical features, diagnosis, and treatment of LUSC patients with intestinal metastasis and present a rare case of LUSC with intestinal metastasis. We describe a patient who presented with a severe cough and chest pain and diagnosed with LUSC and bone tumor. Initially, the primary LUSC and bone tumor were controlled with standard treatments. However, the primary LUSC reoccurred shortly after treatment, this time with intestinal metastasis, for which effective treatments are lacking. Our observation from the case suggests that LUSC metastasizing to intestinal tract is associated with a poorer prognosis. Lung squamous cell carcinoma (LUSC), accounting for 20%-30% of non-small cell lung cancer (NSCLC) cases, is associated with high mortality. In its early stages, the symptoms of LUSC are mild and often go unnoticed. Consequently, most patients are diagnosed at an advanced stage. Intestinal metastasis from lung cancer is a relatively rare occurrence. Clinically, diagnosing intestinal metastasis of LUSC primarily relies on imaging examination results. Here, we review the clinical features, diagnosis, and treatment of LUSC patients with intestinal metastasis and report a rare case of LUSC accompanied by intestinal metastasis.image