Re-salvage focal low-dose rate brachytherapy for local recurrence of prostate cancer after salvage focal low-dose rate brachytherapy

被引:0
|
作者
Nakamoto, Takahiro [1 ,4 ]
Yoshida, Takashi [1 ]
Shiga, Toshiko [2 ]
Taguchi, Makoto [3 ]
Mishima, Takao [3 ]
Kawakita, Shigenari [3 ]
Murota, Takashi [3 ]
Kinoshita, Hidefumi [1 ]
机构
[1] Kansai Med Univ, Dept Urol & Androl, Osaka, Japan
[2] Kansai Med Univ, Med Ctr, Dept Radiol, Osaka 5700074, Japan
[3] Kansai Med Univ, Med Ctr, Dept Urol & Androl, Osaka, Japan
[4] 2-5-1 Shinmachi, Hirakata, Osaka 5731191, Japan
关键词
brachytherapy; local recurrence; salvage therapy; RADIOTHERAPY;
D O I
10.1002/iju5.12670
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
IntroductionSalvage brachytherapy represents an effective treatment for local recurrence of prostate cancer after prior external beam radiotherapy. However, the optimal therapeutic strategies for local recurrence after salvage brachytherapy have not yet been determined.Case presentationWe describe the case of a 77-year-old man who underwent re-salvage focal low-dose rate brachytherapy for local recurrence after carbon ion radiotherapy and salvage focal low-dose rate brachytherapy. We performed re-salvage focal low-dose rate brachytherapy for the recurrence with a different type of seed, which resulted in a significant reduction in the prostate-specific antigen level. During the 35-month follow-up after re-salvage focal low-dose rate brachytherapy, no recurrence of prostate cancer and no severe radiation-related toxicities were observed.ConclusionOur patient was successfully treated with re-salvage focal low-dose rate brachytherapy for local recurrence after salvage focal low-dose rate brachytherapy. This treatment strategy might be effective for such patients and is not associated with sexual dysfunction or severe adverse events.
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页码:68 / 72
页数:5
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