Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea

被引:1
|
作者
Choi, Chi-Hwan [1 ]
Lee, Minji [1 ]
Lee, Sang Eun [1 ]
Kim, Jin-Won [1 ]
Shin, Hwachul [1 ]
Choi, Myung-Min [1 ]
Yi, Hwajung [1 ]
Kim, Min-Kyung [2 ]
Jeon, Jaehyun [2 ]
Park, Jun-Sun [3 ]
Kim, Yeonjae [2 ]
Lim, So Yun [2 ]
Chin, Bumsik [2 ]
Chung, Yoon-Seok [1 ,2 ,4 ]
机构
[1] Korea Dis Control & Prevent Agcy, Cheongju, South Korea
[2] Natl Med Ctr, Dept Internal Med, Div Infect Dis, Res Bldg R615,245 Eulji Ro, Seoul 04564, South Korea
[3] Publ Hlth Res Inst, Natl Med Ctr, Seoul, South Korea
[4] Korea Dis Control & Prevent Agcy, Div High Risk Pathogens, Bur Infect Dis Diag Control, 187 Osongsaengmyeong 2 Ro, Cheongju 28159, South Korea
关键词
Mpox; Monkeypox Virus; Genomic Analysis; Agency (KDCA) press report;
D O I
10.3346/jkms.2024.39.e165
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far East isolates (the Republic of Korea, Japan, and Taiwan), distinguishing them from the diverse lineages found in the Americas, Europe, Africa, and Oceania. In early 2023, the prevalence of the B.1.3 lineage of monkeypox virus identified in six patients with no overseas travel history is considered as an indicator of the potential initiation of local transmission in the Republic of Korea.
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页数:5
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