Association between Lipoprotein(a) concentration and adverse cardiac events in patients with coronary artery disease: An observational cohort study

被引：0
|
作者：
Amin, Navaneeth [1 ]
Devasia, Tom [1 ]
Kamath, Shobha Ullas [2 ]
Paramasivam, Ganesh [1 ]
Shetty, Prasad Narayana [1 ]
Singh, Ajit [3 ]
Prakash, N. S. Ganesha [1 ]
机构：
[1] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Cardiol, Manipal, Karnataka, India
[2] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Biochem, Manipal, Karnataka, India
[3] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Med, Manipal, Karnataka, India
来源：
INDIAN HEART JOURNAL | 2024年 / 76卷 / 03期
关键词：
Coronary artery disease; Lipoprotein(a); Adverse cardiac events; RISK;
D O I：
10.1016/j.ihj.2024.06.001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This prospective study investigated the association between lipoprotein (a) [Lp(a)] levels and adverse cardiac events in patients undergoing percutaneous coronary intervention (PCI) for coronary artery disease. Among 600 patients, 79.16 % were male. Kaplan Meier analysis revealed significantly higher incidence rates of cardiac death, major adverse cardiac events, myocardial infarction, revascularization and stroke in patients with elevated Lp(a) (>= 30 mg/dL). The Cox Regression model identified Lp(a) >= 30 mg/dL as a significant risk factor for adverse events (HR: 4.2920; 95%CI: 2.58-7.120; p < 0.05). Elevated Lp(a) levels were associated with an increased risk of adverse cardiac events in coronary artery disease patients undergoing PCI.
引用
收藏
页码：197 / 201
页数：5
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