Quality of life, mood disorders, and cognitive impairment in adults with 8-thalassemia

被引：1

作者：

Bizri, Maya ^{[1
]}

Koleilat, Rawan ^{[1
]}

Akiki, Nathalie ^{[2
]}

Dergham, Reem ^{[1
]}

Mihailescu, Alexandra Monica ^{[3
]}

Bou-Fakhredin, Rayan ^{[4
]}

Musallam, Khaled M. ^{[5
]}

Taher, Ali T. ^{[6
,7
]}

机构：

[1] Amer Univ Beirut, Med Ctr, Dept Psychiat, Beirut, Lebanon

[2] Kings Coll Hosp London, Dept Haematol, London, England

[3] AK & Kind, Bucharest, Romania

[4] Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy

[5] Burjeel Med City, Ctr Res Rare Blood Disorders CR RBD, Abu Dhabi, U Arab Emirates

[6] Amer Univ Beirut, Med Ctr, Dept Internal Med, Beirut, Lebanon

[7] Amer Univ Beirut, Naef K Basile Canc Inst, Dept Internal Med, Med Ctr,Med Hematol & Oncol, POB 11-0236, Beirut 11072020, Lebanon

来源：

BLOOD REVIEWS | 2024年 / 65卷

关键词：

QoL; Depression; Anxiety; Suicide; Cognition; Psychiatry; BETA-THALASSEMIA MAJOR; SILENT CEREBRAL-ISCHEMIA; SPLENECTOMIZED ADULTS; PSYCHIATRIC-DISORDERS; HOSPITAL ANXIETY; DEPRESSION SCALE; CHILDREN; HEALTH; TRANSFUSION; ADOLESCENTS;

D O I：

10.1016/j.blre.2024.101181

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Advances in understanding the disease process in 8-thalassemia supported development of various treatment strategies that resulted in improved survival. Improved survival, however, allowed multiple morbidities to manifest and cemented the need for frequent, lifelong treatment. This has directly impacted patients' healthrelated quality of life and opened the door for various psychiatric and cognitive disorders to potentially develop. In this review, we summarize available evidence on quality of life, depression and anxiety, suicidality, and cognitive impairment in adult patients with 8-thalassemia while sharing our personal insights from experience in treating patients with both transfusion-dependent and non-transfusion-dependent forms.

引用

页数：7

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