Case Report: Radiation necrosis mimicking tumor progression in a patient with extranodal natural killer/T-cell lymphoma

被引:0
|
作者
Chen, Boxiao [1 ]
Fan, Yili [1 ]
Wang, Luyao [1 ]
Zhang, Jiawei [1 ]
Xin, Dijia [1 ]
Qiu, Xi [1 ]
Jiang, Huawei [1 ]
Li, Baizhou [2 ]
Chen, Qin [2 ]
Wang, Chao [3 ]
Xiao, Xibin [1 ]
Huang, Liansheng [1 ]
Xu, Yang [1 ,4 ]
机构
[1] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Hematol, Hangzhou, Peoples R China
[2] Zhejiang Univ, Affiliated Hosp 2, Dept Pathol, Sch Med, Hangzhou, Peoples R China
[3] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Radiol, Hangzhou, Peoples R China
[4] Zhejiang Univ, Life Sci Inst, Zhejiang Prov Key Lab Canc Mol Cell Biol, Hangzhou, Peoples R China
来源
FRONTIERS IN RADIOLOGY | 2023年 / 3卷
关键词
radiation necrosis; secondary central nervous system lymphoma; extranodal natural killer/T-cell lymphoma; radiation therapy; radiological examination; RECURRENT; GLIOMAS;
D O I
10.3389/fradi.2023.1257565
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Radiation-induced cerebral necrosis, also known as radiation encephalopathy, is a debilitating condition that significantly impacts the quality of life for affected patients. Secondary central nervous system lymphoma (SCNSL) typically arises from highly aggressive mature B-cell lymphoma, but rarely from extranodal natural killer T-cell lymphoma (ENKTL). Treatment will be guided by differentiation between lymphoma progression from brain necrosis, and is particularly important for critically ill patients in an acute setting. However, differential diagnosis remains challenging because they share similar clinical manifestations and have no specific imaging features. We present the case of a 52-year-old man with ENKTL who suffered an emergency brain herniation secondary to massive radiation necrosis. The diagnosis established by brain biopsy ultimately led to appropriate treatment. The importance of the diagnostic biopsy is highlighted in this case for distinguishing between radiation necrosis and SCNSL.
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页数:6
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