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Reducing racial and ethnic disparities in cardiovascular outcomes among cancer survivors
被引:0
|作者:
Tan, Min Choon
[1
,2
]
Stabellini, Nickolas
[3
,4
,5
,6
]
Tan, Jia Yi
[1
]
Thong, Jia Yean
[7
]
Hedrick, Catherine
[3
]
Moore, Justin Xavier
[8
]
Cullen, Jennifer
[9
]
Hines, Anika
[10
]
Sutton, Arnethea
[10
]
Sheppard, Vanessa
[10
]
Agarwal, Neeraj
[11
]
Guha, Avirup
[3
,5
]
机构:
[1] New York Med Coll, Dept Internal Med, St Michaels Med Ctr, Newark, NJ USA
[2] Mayo Clin, Dept Cardiovasc Med, Phoenix, AZ USA
[3] Augusta Univ, Dept Cardiovasc Med, Med Coll Georgia, Augusta, GA 30912 USA
[4] Case Western Reserve Univ, Sch Med, Cleveland, OH USA
[5] Univ Hosp Seidman Canc Ctr, Dept Hematol Oncol, Cleveland, OH 44106 USA
[6] Hosp Israelita Albert Einstein, Fac Israelita Ciencias Saude Albert Einstein, Sao Paulo, SP, Brazil
[7] Fudan Univ, Shanghai Med Coll, Shanghai, Peoples R China
[8] Univ Kentucky, Coll Med, Lexington, KY USA
[9] Case Western Reserve Univ, Cleveland, OH USA
[10] Virginia Commonwealth Univ, Richmond, VA USA
[11] Univ Utah, Salt Lake City, UT USA
关键词:
Racial disparities;
Cardio-oncology;
Cardiovascular outcomes;
Cancer survivors;
HEALTH DISPARITIES;
RISK-FACTORS;
SCIENTIFIC STATEMENT;
SOCIAL DETERMINANTS;
CARDIO-ONCOLOGY;
DNA METHYLATION;
AMERICAN;
DISEASE;
ACCULTURATION;
INFLAMMATION;
D O I:
10.1007/s11912-024-01578-7
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Purpose of reviewAnalyze current evidence on racial/ethnic disparities in cardiovascular outcomes among cancer survivors, identifying factors and proposing measures to address health inequities.Recent findingsExisting literature indicates that the Black population experiences worse cardiovascular outcomes following the diagnosis of both initial primary cancer and second primary cancer, with a notably higher prevalence of cardio-toxic events, particularly among breast cancer survivors. Contributing socioeconomic factors to these disparities include unfavorable social determinants of health, inadequate insurance coverage, and structural racism within the healthcare system. Additionally, proinflammatory epigenetic modification is hypothesized to be a contributing genetic variation factor. Addressing these disparities requires a multiperspective approach, encompassing efforts to address racial disparities and social determinants of health within the healthcare system, refine healthcare policies and access, and integrate historically stigmatized racial groups into clinical research.SummaryRacial and ethnic disparities persist in cardiovascular outcomes among cancer survivors, driven by multifactorial causes, predominantly associated with social determinants of health. Addressing these healthcare inequities is imperative, and timely efforts must be implemented to narrow the existing gap effectively.
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