Long Objective Sleep Duration is a Marker of Cognitive Impairment in Older Adults: Findings from the Cretan Aging Cohort

被引:0
|
作者
Basta, Maria [1 ,2 ,3 ]
Bouloukaki, Izolde [4 ]
Skourti, Eleni [1 ]
Zampetakis, Alexandros [1 ]
Alexopoulou, Christina [5 ]
Ganiaris, Andronikos [1 ]
Aligizaki, Marina [1 ]
Zaganas, Ioannis [6 ]
Simos, Panagiotis [1 ]
Vgontzas, Alexandros [1 ,2 ]
机构
[1] Univ Hosp Heraklion, Dept Psychiat, Iraklion 71500, Crete, Greece
[2] Penn State Univ, Dept Psychiat & Behav Hlth, Sleep Res & Treatment Ctr,Coll Med, Penn State Hlth Milton S Hershey Med Ctr, Hershey, PA USA
[3] Univ Hosp Heraklion, Day Care Ctr Alzheimers Dis PAGNH Nefeli, Iraklion, Greece
[4] Univ Crete, Dept Social & Family Med, Iraklion, Greece
[5] Univ Hosp Herakl, Dept Intens Care Unit, Iraklion, Greece
[6] Univ Hosp Herakl, Dept Neurol, Iraklion, Greece
关键词
Alzheimer's disease; cognitive performance; dementia; long sleep duration; mild cognitive impairment; older adults; SELF-REPORTED SLEEP; DEMENTIA; INFLAMMATION; METAANALYSIS; ASSOCIATION; PERFORMANCE; BETA;
D O I
10.3233/ADR-230203
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We examined associations between objective sleep duration and cognitive status in older adults initially categorized as cognitively non-impaired (CNI, n = 57) or diagnosed with mild cognitive impairment (MCI, n = 53). On follow-up, 8 years later, all participants underwent neuropsychiatric/neuropsychological evaluation and 7-day 24-h actigraphy. On re-assessment 62.7% of participants were cognitively declined. Patients who developed dementia had significantly longer night total sleep time (TST) than persons with MCI who, in turn, had longer night TST than CNI participants. Objective long sleep duration is a marker of worse cognitive status in elderly with MCI/dementia and this association is very strong in older adults.
引用
收藏
页码:927 / 934
页数:8
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