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Reverse transcription of HIV-1 2-LTR circle transcripts does frequently cause 3'-polypurine tract mutations implicated in dolutegravir resistance

被引：0
|
作者：
Dekker, Jose G. [1 ,2 ]
Klaver, Bep [1 ,2 ]
Berkhout, Ben [1 ,2 ]
Das, Atze T. [1 ,2 ]
机构：
[1] Univ Amsterdam, Med Microbiol & Infect Prevent, Amsterdam UMC, Amsterdam, Netherlands
[2] Amsterdam Inst Immunol & Infect Dis, Amsterdam, Netherlands
来源：
JOURNAL OF VIROLOGY | 2024年 / 98卷 / 06期
基金：
美国国家卫生研究院;
关键词：
HIV-1; drug-resistance evolution; dolutegravir; drug resistance mechanisms; GENE-EXPRESSION; STRAND TRANSFER; REPLICATION; EXTENSION; INTEGRASE;
D O I：
10.1128/jvi.00335-24
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
引用
收藏
页数：5
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