Data on characteristics of simplicia, phytoconstituents, and antioxidant activity of Moringa oleifera leaves ethanol extract

The article reports data on the chemical and pharmacological characteristics of Moringa oleifera simplicia and ethanol extract consisting of water content, acid -insoluble ash content, microbial contamination, heavy metal contamination, phytochemical analysis, TLC analysis, chemical profiling using LCMS/MS, and the antioxidant activity. The M. oleifera leaves simplicia meet quality standards, except for ash content that exceeds the specified standards. Qualitative phytochemistry indicates that the ethanol extract of M. oleifera leaves contains flavonoids, tannins, and steroids. In total of 39 phytoconstituents were tentatively identified; the top 10 active compounds with the highest relative abundance percentage (%) are 4-undecylbenzenesulfonic acid (4,83), apigetrin (3,34), quercetin-3 beta -D-glucoside (3,28), D-(-)-quinic acid (1,69), corchorifatty acid F (1,52), 4-hydroxybenzaldehyde (1,47), isopropylmalic acid (1,17), 13( S )-HOTrE (1,08), astragalin (0,99), and D-( + )-phenyllactic acid (0,70). The ethanol extract of M. oleifera leaves contained a total phenolic content 7728,02 mg/kg, total flavonoids as quercetin content 1,19%, and antioxidant activity IC 50 1422,45 mg/kg. (c) 2024 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/ )