Cancer metastasis and stemness: The metastasis-inducer MACC1 regulates LGR5 to promote cancer stem cell-like properties in colorectal cancer

被引：0
|
作者：
Erdem, Muge
Lee, Kyung Hwan
Hardt, Markus
Regan, Joseph
Kobelt, Dennis
Walther, Wolfgang
Regenbrecht, Christian
Stein, Ulrike S.
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 06期
关键词：
D O I：
10.1158/1538-7445.AM2024-1566
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1566
引用
收藏
页数：2
相关论文
共 50 条
  • [1] MACC1 Regulates LGR5 to Promote Cancer Stem Cell Properties in Colorectal Cancer
    Erdem, Muege
    Lee, Kyung Hwan
    Hardt, Markus
    Regan, Joseph L.
    Kobelt, Dennis
    Walther, Wolfgang
    Mokrizkij, Margarita
    Regenbrecht, Christian
    Stein, Ulrike
    CANCERS, 2024, 16 (03)
  • [2] LGR5 suppresses colon cancer metastasis
    Zhou, Xiaolin
    Wang, Jing Jenny
    CANCER RESEARCH, 2015, 75
  • [3] Metastasis associated in colon cancer 1 (MACC1): at the crossroads of cancer metastasis and drug resistanced
    Guo, Tao
    Gu, Chundong
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 11 (10): : 10355 - 10363
  • [4] Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer
    Juneja, Manisha
    Ilm, Katharina
    Schlag, Peter M.
    Stein, Ulrike
    MOLECULAR ONCOLOGY, 2013, 7 (05): : 929 - 943
  • [5] Tyrosine phosphorylation of MACC1 is essential and druggable for colorectal cancer metastasis restriction
    Kobelt, Dennis
    Dittmar, Gunnar
    Fleuter, Claudia
    Smith, Janice
    Dahlmann, Mathias
    Migotti, Rebekka
    Schlag, Peter M.
    Stein, Ulrike S.
    CANCER RESEARCH, 2015, 75
  • [6] Lgr5 promotes cancer stemness and confers chemoresistance through ABCB1 in colorectal cancer
    Liu, Yi-Shiuan
    Hsu, Hung-Chih
    Tseng, Kai-Chi
    Chen, Hua-Chien
    Chen, Shu-Jen
    BIOMEDICINE & PHARMACOTHERAPY, 2013, 67 (08) : 791 - 799
  • [7] Metastasis associated in colon cancer 1 (MACC1) promotes growth and metastasis processes of colon cancer cells
    Tang, J.
    Chen, J. -X.
    Chen, L.
    Tang, J. -Y.
    Cui, Z.
    Liu, C. -H.
    Wang, Z.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2016, 20 (13) : 2825 - 2834
  • [8] LGR5 positivity defines stem-like cells in colorectal cancer
    Hirsch, Daniela
    Barker, Nick
    McNeil, Nicole
    Hu, Yue
    Camps, Jordi
    McKinnon, Katherine
    Clevers, Hans
    Ried, Thomas
    Gaiser, Timo
    CARCINOGENESIS, 2014, 35 (04) : 849 - 858
  • [9] The MACC1 interactome is involved in receptor tyrsoine kinase signaling of colorectal cancer metastasis
    Zincke, F.
    Kobelt, D.
    Klaeger, S.
    Pachl, F.
    Frejno, M.
    Feller, S. M.
    Kuster, B.
    Stein, U.
    ONCOLOGY RESEARCH AND TREATMENT, 2018, 41 : 56 - 56
  • [10] Colon cancer metastasis: MACC1 and Met as metastatic pacemakers
    Arlt, Franziska
    Stein, Ulrike
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2009, 41 (12): : 2356 - 2359
12345