A review of the clinical experience in pulsed dose rate brachytherapy

被引：16
|
作者：
Balgobind, Brian V. [1 ,2 ]
Koedooder, Kees [1 ]
Zuniga, Diego Ordonez [1 ]
Fajardo, Raquel Davila [1 ]
Rasch, Coen R. N. [1 ]
Pieters, Bradley R. [1 ]
机构：
[1] Univ Amsterdam, Acad Med Ctr, Dept Radiat Oncol, NL-1105 AZ Amsterdam, Netherlands
[2] Vrije Univ Amsterdam Med Ctr, Dept Radiat Oncol, Amsterdam, Netherlands
来源：
BRITISH JOURNAL OF RADIOLOGY | 2015年 / 88卷 / 1055期
关键词：
EXTERNAL-BEAM RADIOTHERAPY; PARTIAL BREAST IRRADIATION; SOFT-TISSUE SARCOMAS; INTENSITY-MODULATED BRACHYTHERAPY; DEFINITIVE TREATMENT MODALITY; TANDEM-OVOID APPLICATORS; UTERINE CERVIX CARCINOMA; FRENCH COOPERATIVE GROUP; SQUAMOUS-CELL CARCINOMA; RATE PDR BRACHYTHERAPY;
D O I：
10.1259/bjr.20150310
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Pulsed dose rate (PDR) brachytherapy is a treatment modality that combines physical advantages of high dose rate (HDR) brachytherapy with the radiobiological advantages of low dose rate brachytherapy. The aim of this review was to describe the effective clinical use of PDR brachytherapy worldwide in different tumour locations. We found 66 articles reporting on clinical PDR brachytherapy including the treatment procedure and outcome. Moreover, PDR brachytherapy has been applied in almost all tumour sites for which brachytherapy is indicated and with good local control and low toxicity. The main advantage of PDR is, because of the small pulse sizes used, the ability to spare normal tissue. In certain cases, HDR resembles PDR brachytherapy by the use of multifractionated low-fraction dose.
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页数：18
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