共 50 条
- [1] First in Human phase 1/2a trial of a macrocyclic ATR inhibitor (ATRN-119) in patients with advanced solid tumors[J]. MOLECULAR CANCER THERAPEUTICS, 2023, 22 (12)Simpkins, FionaSchneider, RevaMahipal, AmitLoRusso, PatriciaMiller, CrystalBrown, EricCarleton, MikeGullbo, JoachimMirza, Nadeem Q.
- [2] Phase 1 first-in-human trial of MTB-9655, the first oral inhibitor of ACSS2, in patients with advanced solid tumors.[J]. JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)Perets, RuthGeva, RavitMcKean, MeredithGoutopoulos, AndreasErez, OmriPhadnis, MonicaYoussoufian, HagopSchwartz, Brian E.Kansra, VikramFattaey, Ali
- [3] First-In-Human, First-In-Class, Phase I Trial of the Fucosylation Inhibitor SGN-2FF in Patients with Advanced Solid Tumors[J]. ONCOLOGIST, 2021, 26 (11): : 925 - +Do, Khanh T.Chow, Laura Quan ManReckamp, KarenSanborn, Rachel E.Burris, HowardRobert, FranciscoCamidge, D. RossSteuer, Conor E.Strickler, John H.Weise, AmySpecht, Jennifer M.Gutierrez, MartinHaughney, PeterHengel, ShawnaDerleth, Christina LouiseYap, Timothy A.
- [4] First-in-human phase I study of the microtubule inhibitor plocabulin in patients with advanced solid tumors[J]. Investigational New Drugs, 2019, 37 : 674 - 683Elena ElezCarlos Gomez-RocaArturo Soto Matos-PitaGuillem ArgilesThibaud ValentinCinthya CoronadoJorge IglesiasTeresa MacarullaSarah BetrianSalvador FudioKatrin ZaragozaJosep TaberneroJean-Pierre Delord
- [5] First-in-human phase I study of the microtubule inhibitor plocabulin in patients with advanced solid tumors[J]. INVESTIGATIONAL NEW DRUGS, 2019, 37 (04) : 674 - 683Elez, ElenaGomez-Roca, CarlosSoto Matos-Pita, ArturoArgiles, GuillemValentin, ThibaudCoronado, CinthyaIglesias, JorgeMacarulla, TeresaBetrian, SarahFudio, SalvadorZaragoza, KatrinTabernero, JosepDelord, Jean-Pierre
- [6] A first-in-human phase I trial of AR-12, a PDK-1 inhibitor, in patients with advanced solid tumors.[J]. JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)Mateo, JoaquinDe Bono, Johann SebastianRamanathan, Ramesh K.Lustberg, Maryam B.Zivi, AndreaBasset, DawnNg, MatthewYoung, Anna-MaryGarrett, MichelleDecordova, ShaunRaynaud, Florence I.Yap, Timothy AnthonyZukiwski, Alexander A.Proniuk, StefanShapiro, Charles L.
- [7] A first-in-human phase I study of ATR inhibitor M1774 in patients with solid tumors.[J]. JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)Yap, Timothy A.Tolcher, Anthony W.Plummer, Elizabeth RuthBecker, AndreasFleuranceau-Morel, PatriciaGoddemeier, ThomasLocatelli, GiuseppeGounaris, IoannisDe Bono, Johann S.
- [8] A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas[J]. CLINICAL CANCER RESEARCH, 2012, 18 (12) : 3396 - 3406Hong, David S.Kurzrock, RazelleSupko, Jeffrey G.He, XiaoyingNaing, AungWheler, JenniferLawrence, DonaldEder, Joseph PaulMeyer, Colin J.Ferguson, Deborah A.Mier, JamesKonopleva, MarinaKonoplev, SergejAndreeff, MichaelKufe, DonaldLazarus, HillardShapiro, Geoffrey I.Dezube, Bruce J.
- [9] First-in-Human Trial of the Oral Ataxia Telangiectasia and RAD3-Related (ATR) Inhibitor BAY 1895344 in Patients with Advanced Solid Tumors[J]. CANCER DISCOVERY, 2021, 11 (01) : 80 - 91Yap, Timothy A.Tan, David S. P.Terbuch, AngelikaCaldwell, ReeceGuo, ChristinaGoh, Boon CherHeong, ValerieHaris, Noor R. MdBashir, SairaDrew, YvetteHong, David S.Meric-Bernstam, FundaWilkinson, GaryHreiki, JosephWengner, Antje M.Bladt, FriedhelmSchlicker, AndreasLudwig, MatthiasZhou, YinghuiLiu, LiBordia, SonalPlummer, RuthLagkadinou, Elenide Bono, Johann S.
- [10] First-in-human study of ATR inhibitor IMP9064 monotherapy and in combination with PARP inhibitor senaparib in patients with advanced solid tumors[J]. ANNALS OF ONCOLOGY, 2023, 34 : S476 - S477Lin, C-C.Schneider, R. E.Gutierrez, M.Shen, L.Gao, B.Chung, K.Doroshow, D. B.Millward, M.Hsieh, C-Y.Xu, C.Cai, S. X.Tian, Y. E.Liu, L.Shen, C.Li, B.Tan, Y.Zhang, C.Li, L.Ma, M.Chen, X.