Precision Targeting of the Gut Microbiome for Cancer Immunotherapy

被引：0

作者：

Lombardi, Pasquale ^{[1
]}

Pinato, David J. ^{[1
,2
]}

机构：

[1] Imperial Coll London, Hammersmith Hosp, Dept Surg & Canc, Div Canc, Du Cane Rd, London W12 0HS, England

[2] Univ Piemonte Orientale, Dept Translat Med, Div Oncol, Novara, Italy

来源：

CANCER DISCOVERY | 2024年 / 14卷 / 07期

关键词：

D O I：

10.1158/2159-8290.CD-24-0538

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Transforming gut microbial status from a prognostic trait to a therapeutic target is a key goal to understand and reverse resistance to anticancer immunotherapy. Glitza and colleagues propose selective manipulation of the gut microbiome with SER401 following antibiotic preconditioning and highlight multiple challenges in delivering microbiome manipulation to the clinic.

引用

页码：1140 / 1142

页数：3

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